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« En tant que femme et gynécologue médicale, je voudrais apporter, dans ce livre, un témoignage clair et objectif, personnel, pour ne pas dire “engagé”, sur l’histoire tourmentée du traitement hormonal de la ménopause et de ses polémiques dévastatrices sans fin auxquelles j’ai assisté depuis trente ans. Il existe de véritables avantages du THS que l’on a eu tendance à gommer au profit des risques encourus largement amplifiés. » A. de K. Autour de la cinquantaine, arrivées à une étape clef de la vie, beaucoup de femmes s’interrogent : faut-il oui ou non suivre un traitement hormonal substitutif ? Quels sont ses bienfaits et ses risques éventuels ? A-t-il des effe...
A two-edged sword of reconciliation and betrayal, Chinook Jargon (aka Wawa) arose at the interface of “Indian” and “White” societies in the Pacific Northwest. Wawa’s sources lie first in the language of the Chinookans who lived along the lower Columbia River, but also with the Nootkans of the outer coast of Vancouver Island. With the arrival of the fur trade, the French voyageurs provided additional vocabulary and cultural practices. Over the next decades, ensuing epidemics and the Oregon Trail transformed the Chinookans and their homeland, and Wawa became a diaspora language in which many communities seek some trace of their past. A previously unpublished glossary of Wawa circa 1825 is included as an appendix to this volume.
The fundamental relationship between the neuropathological lesions of Alzheimer's disease and the problem of what underlies the clinical syndrome has remained unsolved since the beginning of the century. Are neurofibrillary tangles and senile plaques directly related to clinical symptoms, or are they epiphenomena that signal synaptic and neuronal loss? In the last decade, these questions have been revisited through systematic studies of individuals with various degrees of dementia using newer immunohistochemical techniques and quantitative approaches to neuropathological study. It is now possible to have a uniform picture of Alzheimer's disease dementia as resulting from collapse of specific neural systems, as pathological changes selectively and specifically involve structures related to memory and higher cognitive functions.This book contains the proceedings of a meeting organized by the Fondation Ipsen which brought together researchers in neuropathology, molecular biology, genetics, neuropsychology, brain imagery and clinical neurology. .
Archibald McDonald was one of the most important fur traders in the region west of the Rockies. He is particularly remembered as a factor at Forts Langley, Kamloops, and Colville, and as one of the traders who enabled the Hudson's Bay Company to gain control of the vast region west of the Rockies. A pioneer cartographer, he also prepared the first censuses of Kamloops and Fort Langley. In this informative and entertaining collection of letters, his life as a factor, family man, amateur naturalist, and close observer of everything going on around him provides an invaluable glimpse of both the man and the Pacific Northwest.
Jean Barman was the recipient of the 2014 George Woodcock Lifetime Achievement Award. In French Canadians, Furs, and Indigenous Women in the Making of the Pacific Northwest, Jean Barman rewrites the history of the Pacific Northwest from the perspective of French Canadians attracted by the fur economy, the indigenous women whose presence in their lives encouraged them to stay, and their descendants. Joined in this distant setting by Quebec paternal origins, the French language, and Catholicism, French Canadians comprised Canadiens from Quebec, Iroquois from the Montreal area, and métis combining Canadien and indigenous descent. For half a century, French Canadians were the largest group of newcomers to this region extending from Oregon and Washington east into Montana and north through British Columbia. Here, they facilitated the early overland crossings, drove the fur economy, initiated non-wholly-indigenous agricultural settlement, eased relations with indigenous peoples, and ensured that, when the region was divided in 1846, the northern half would go to Britain, giving today’s Canada its Pacific shoreline.
This directory is a handy on-volume discovery tool that will allow readers to locate rare book and special collections in the British Isles. Fully updated since the second edition was published in 1997. this comprehensive and up-to-date guide encompasses collections held in libraries, archives, museums and private hands. The Directory: Provides a national overview of rare book and special collections for those interested in seeing quickly and easily what a library holds Directs researchers to the libraries most relevant for their research Assists libraries considering acquiring new special collections to assess the value of such collections beyond the institution,showing how they fit into a ‘unique and distinctive’ model. Each entry in the Directory provides background information on the library and its purpose, full contact details, the quantity of early printed books, information about particular subject and language strengths, information about unique works and important acquisitions, descriptions of named special collections and deposited collections. Readership: Researchers, academic liaison librarians and library managers.
These journals comprise one of the principal sources of information on early European settlement in BC and provide a remarkable and unique record of the establishment of Fort Langley. Although the journals record such day-to-day details as weather, trade, and visitors, they also contain a wealth of information about social and administrative life at the fort.
List of members in 1875-76.