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Gamma Knife Neurosurgery
Today, over 500,000 patients have been treated world wide in 250 Gamma Knife Centres in 37 countries each one treating between 150 and 700 patients a year. The current book serves as a textbook, training manual and reference book for those involved in Gamma Knife practice covering the theoretical background, the practical aspects of treatment, the social side of the method and necessary information not only for users but for those who refer to the Gamma Knife. It also covers some aspects of the hospital and social administration required for optimal use of the technology, also looking at the effect of the internet on specialist medical practice. It also presents the completely new Gamma Knife (Perfexion), a new technology which extends the range of the Gamma Knife and will be the treatment standard for the future.
Gamma Knife Surgery
Radiosurgery has become an established technique, with more than 15000 patients treated world-wide, most of them in the last five years. Yet, there is much uncertainty in the general medical community as to the nature, advantages and limitations of the method. This uncertainty provokes unnecessary debate between colleagues and is a source of avoidable stress to patients. This book provides an account of the scientific basis of radiosurgery and describes its current applications in respect of the only well established radiosurgical device, the Leksell Gamma Knife. The book assumes the general medical knowledge of a newly qualified medical practitioner. There are three sections. The first outl...
Immuno-oncology and immunotherapy Part C
Immuno-oncology and immunotherapy, Part C, Volume 191 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Extraction and quantification of histones from human cells, Expression and characterization of Phosphatidylserine-targeting antibodies for biochemical and therapeutic applications, ILC differentiation from HSCs in vitro, Methods to expand human Treg cells and assay their function, Monitoring rapid activation of human gamma/delta T cells by multicolor flow cytometry, Methods to induce T cell exhaustion in vitro, Ex vivo assessment of human neutrophil motility and migratio...
Cell Transplantation
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Anticancer Research
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Brain Tumor Invasion
Brain Tumor Invasion Biological, Clinical, and Therapeutic Considerations Edited by Tom Mikkelsen Rolf Bjerkvig Ole Didrik Laerum Mark L. Rosenblum Recent advances in molecular biology have given us profound new insights into the behavior of primary brain tumors. Not only are such tumors more diffuse in their infiltration of brain tissue and therefore less amenable to surgery than brain tumors originating elsewhere in the body—it now appears that the central nervous system and the normal brain itself constitute a biological environment conducive to the uncontrolled spread of primary tumors. Brain Tumor Invasion is the first comprehensive reference devoted to the invasive behavior of primar...
The History of the Gamma Knife
The History of the Gamma Knife presents the evolution of concepts and technology which ended in the production of the modern Gamma Knife. The story starts before the Second World War and links pioneers in Berkeley and Sweden. To the best of the author's belief it is the first detailed, factually accurate account of the development of this important therapeutic method. - The author has been involved in Gamma Knife surgery since the early days and has written 3 books and many papers on the topic - The author is fluent in Scandinavian languages and knows the original pioneers in the field and has consulted with them to ensure the story is accurate - The book is written in an informal easy to read style - The book fills a vacuum in the literature. There are many short accounts of a few pages but no hopefully definitive account of the story of the Gamma Knife. Also these short accounts all too often contain errors which hopefully are absent from the current text
