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The Pharmacology of Sexual Function and Dysfunction
The pharmaceutical industry has, over the past decade, renewed it's interest in the search for sexually enhancing drugs, mainly with a view to finding pharmacological agents which might prove useful in the clinical management of sexual problems. An additional issue, of increasing importance, is the occurrence of sexual side effects from modern pharmacological treatments. in humans remains unclear. The animal data outlined in this proceedings show us that brain mechanisms relevant to sexuality are also involved in other types of appetitive behaviour, and whether there is a specific pharmacology of sexual function remains a key question. the animal and human fields of sexual pharmacology were brought together. The interaction between them, found in the edited discussions of this publication, adds a useful dimension to their individual papers.
The Clinical Pharmacology of Sport and Exercise
Hardbound. The problem of drug misuse is one that has concerned governing bodies in sport for nearly three decades. The use of drugs for ergogenic purposes becomes an issue of public concern.This symposium provided a forum for the collation of scientific evidence about the links between drugs and exercise. These proceedings describe the biological context in which drugs have an ergogenic or ergolytic consequence, the interactions between drugs and training effects and the risks to health of chronic drug use.
The Pharmacology of Cell Differentiation
The proceedings of the Esteve Foundation Symposium V, held in Mallorca in 1992, provide a progress report on work in cancer therapy, one of the frontiers of contemporary pharmacology. It includes chapters on the role of Ras proteins in T-cell activation and the design of differentiation therapies.
Variability in Human Drug Response
Hardbound. Variability in Human Drug Response represents a comprehensive account of the information shared by the participants of the Esteve Foundation's Eight Symposium held in Sitges, Spain. The Esteve Foundation which operates independently of any pharmaceutical enterprise, organizes international multidisciplinary meetings like The Esteve Foundation Symposia whose main goal is to stimulate progress in pharmacotherapy through scientific communication and discussion. The 8th symposium provided a timely forum which took into account the many aspects of variability in human drug response. The fact that every patient is different indicates the reason why the art and science of medical diagnosis is so interesting. The diversity in treatment can be viewed both as a challenge and as an obstacle. Clinical pharmacologists have been dealing with the challenge of understanding the many sources of variability in drug responses. With the advent of mo
Molecular Biology and Pharmacology of Tissue Repair
Diseases associated with impaired tissue repair are common clinical problems. Therefore, the elucidation of the molecular basis of normal and impaired repair will help to define new therapeutic targets to alleviate and eventually cure these illnesses. Furthermore, recent studies have revealed remarkable similarities between tissue repair and cancer at the cellular and molecular level. Thus, the characterization of the mechanisms underlying normal repair processes will also enhance our knowledge on the pathogenesis of cancer and provide the basis for the development of novel cancer therapeutics. In recent years, our understanding on the molecular and cellular mechanisms involved in tissue rep...
The Clinical Pharmacology of Biotechnology Products
Researchers in new biology, clinical pharmacologists, physicians, and administrators have bundled their knowledge to produce this enlightening book, covering a broad range of subjects, contributing to helping new biology, through biotechnology, achieve its potential of improving the health of all people everywhere. First, the book takes a general look at biotechnology as a source of drugs. Next is discussed the disposition and pharmacokinetics of peptides and proteins since these differ from the disposition and kinetics of small organic molecules, the traditional types of drugs. Assessing the safety of biotechnology products, and the safety assessment of small organic molecules is also a topic covered by the book, as well as an overview of some of the ways the products of the new biology will have an impact, financially and otherwise, on society.
Optimal Dose Identification
These proceedings provide a general update in an important area of clinical pharmacology; describing how individual subjects vary in their response to drugs and how this information can be used to optimise drug dosing in disease. These proceedings cover areas such as the relevance of studies at various stages of drug development, in optimising drug dosing, the role that pharmacokinetics and pharmacodynamics play and how molecular biology has an increasingly important role in this area. As examples of how these influences may play a role, consideration is given to how drug dosing is optimised in various diseases such as cancer, psychiatric and cardiovascular disease, as well as considering the role that age may play in predicting drug dose. The major theme of this volume is that choosing the optimal dose of a drug has never been more important as risk and benefits must be carefully assessed. There are a series of underlying principles which help determine the optimal dose, and these are dealt with in a systematic manner, using relevant disease states to illustrate these principles.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
