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Interventional Techniques in Cardiovascular Medicine
Since the introduction of balloon angioplasty for the relief of coronary artery stenoses and of anginal symptoms in patients with coronary artery disease by Andreas Griintzig in 1977, the field of interventional technology and treatment strategies has grown enormously. For the reduction of hemodynamically significant coronary artery stenoses balloon angioplasty is the standard and reference method with a high primary success and low complication rate. Because of the relatively high recurrence rates of 30-40% of balloon angioplasty a whole family of different angioplasty techniques has been developed since then. Among those are atherectomy devices, laser angioplasty, radiofrequency angioplast...
The Sinus Node
For the clinician the sinus node is more or less a hidden structure and only by indirect assessment he is able to say something about the function of this center of pacemaker activity. The morphologist, however, is able to describe the structural microscopic and even electronmicroscopic features of this structure. The only disadvantage is that, as soon as he is coming into the picture, the tissue is dead. The physiologist tries to investigate the electrophysiological behavior of the sinus node. Since there is not a human being willing to give his sinus node for research, he has to do his investigation on isolated preparations of animals. Though there are a lot of experts in the field of the sinus node they nearly never speak the same 'language'. Therefore, it was my dream to bring all those people - or at least some of them -together on a workshop. I had the feeling that it was important to organize such a meeting without an audience but only with 'experts'.
The Evaluation of Beat Blocker and Calcium Antagonist Drugs
With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem. Patients requiring medical therapy for hypertension, angina pectoris, arrhythmias, congestive heart failure, and vasospastic disorders of the coronary arteries could receive in the United States only a small number of the drugs available to physicians in the rest of the world. In fact, as the 1980's began, there was only one available beta blocking agent released by The Food and Drug Administration; and even as of this writing, no oral calcium antagonist age...
Infections of Cardiac Implantable Devices
Cardiac implantable device (CIED) infections are a key issue since they have serious consequences in terms of morbidity, mortality and associated costs for healthcare systems. Such infections are highly complex, which has implications for prevention (several factors underlie its development), diagnosis (requiring patient specific integration of several elements), acute treatment (choice of the antibiotic, lead extraction procedure), as well as long-term management (CIED re-implantation strategy and follow-up). Dealing with CIED infections requires appropriate organization of healthcare provision, with the creation of integrated hub-spoke referrals, and it has prompted many of the recent deve...
Clinical Electrocardiography
b>Clinical Electrocardiography Electrocardiography is a transthoracic recording over a period of time. Electrical activity is detected and recorded via electrodes attached to the outer surface of the skin. The recording produced by this noninvasive procedure is termed as electrocardiogram. ECGs are used to measure the rate and regularity of heartbeats as well as the size and position of the chambers, the presence of any damage to the heart, and the effects of drugs or devices used to regulate the heart. Clinical Electrocardiography is the clearest and most accessible guide available to the application and interpretation of the ECG in clinical practice. The book proceeds from the belief that ...
Cardiac Resynchronization Therapy
Cardiac resynchronization therapy (CRT) is one of the most exciting new advances in the treatment of chronic severe (NYHA symptom class) heart failure associated with dyssynchronous ventricular contraction that is refractory to medical treatment. In all randomized trials CR has resulted in improved NYHA symptom class, exercise capacity and quality
Molecular Imaging
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Autonomic Nervous System Dynamics for Mood and Emotional-State Recognition
This monograph reports on advances in the measurement and study of autonomic nervous system (ANS) dynamics as a source of reliable and effective markers for mood state recognition and assessment of emotional responses. Its primary impact will be in affective computing and the application of emotion-recognition systems. Applicative studies of biosignals such as: electrocardiograms; electrodermal responses; respiration activity; gaze points; and pupil-size variation are covered in detail, and experimental results explain how to characterize the elicited affective levels and mood states pragmatically and accurately using the information thus extracted from the ANS. Nonlinear signal processing t...
