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Traditional Chinese medicine has a strong scientific basis, but the science of these important preparations is often rarely discussed. Western approaches often simplify traditional Chinese medicine to drug discovery in Chinese plants, however, the majority of traditional Chinese medications use complex mixtures of plant extracts, rather than single purified drugs. The combination of different extracts is based on yin, yang and chi theories, which are often poorly understood in the West. Yin and yang are known to be the balance of agonists and antagonists, whereas chi derives from signalling processes in the body and regulates bodily functions. Traditional Chinese medical practitioners unders...
This publication represents the views and expert opinion of an IARC Working Group which met in Lyon, 15-22 February 2000.
Walter C. J. ROSS Emeritus Professor, University of London To paraphrase a statement made by Howard E. Skipper many years ago, 'We cancer chemotherapists have often exploited and overworked our chemist colleagues and they have been conveniently forgotten at award giving times'. This book is an attempt to rectify this and highlight the contribution of the chemist in modifying the structure of various types of agent to enhance their effectiveness as inhibitors of the growth of neoplastic tissues. Cancer chemotherapy is a relatively new discipline, coming later than the introduction of sulphonamides and antibiotics. Modern anti-cancer therapy started with the report of the use of a war gas meth...
Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine. This volume presents reviews of traditional Chinese medicine and other plant based therapies useful for treating different cancers. The topics included in this volume are: Herbal extracts from Carica papaya and Azadirachta Natural antimutagens Encapsulated polyphenols and other anticancer compounds derived from plants Traditional Chinese medicine treatments for cancer related fatigue Indirubins Ayurvedic anticancer herbal medicines Melanocyte regeneration through herbal medicine This volume is essential reading for all researchers in the field of natural product chemistry and pharmacology. Medical professionals involved in oncology who seek to improve their knowledge about herbal medicine and alternative therapies will also benefit from the contents of the volume.
This annual review provides critical analysis of the literature on photochemistry and its applications for anyone wanting to keep up to date with the field. Combining reviews on the latest advances in photochemical research with specific topical highlights, this book is the primary resource for anyone wanting succinct and rich information. The volume starts with periodical reports of the recent literature on physical and inorganic aspects, including the molecules of colour, light induced reactions in cryogenic matrices, photobiological systems studied by time-resolved infrared spectroscopy, photophysics and photochemistry of transition metal complexes, recent advances in photocatalytic water...
Antitumor Steroids examines the use of steroids, along with nonsteroidal antiestrogens and some benzo[a]carbazoles, in the treatment of cancer. It explains the mechanism by which steroids and their receptors work together to affect their physiological functions in general and their antitumor activity in particular. It also describes the systematic screening of antitumor compounds isolated from natural sources. Organized into nine chapters, this book begins with an overview of the role of steroids in cancer treatment. It then discusses the estrogens, antiestrogens, and compounds (all containing an aromatic A-ring). The next chapters consider androgens, some antiandrogens, derivatives based on...
This ninetieth volume of the IARC Monographs on the Evaluation of Carcinogenic Risks to Humansconsiders human papillomaviruses (HPVs) which were evaluated by a previous Working Group (IARC, 1995). The monograph in the present volume incorporates new data that have become available during the past decade. HPVs represent the most common infectious agents that are transmitted sexually throughout the world; the major risk factors are behaviors associated with sexual activity. Although most infections are asymptomatic and are cleared within a period of 2 years, genital HPV infection can lead to clinical disease, including anogenital warts, cervical neoplasia, cervical cancer and other anogenital ...
Designed for consumers of risk information, this book offers a balance between the technical and nontechnical literature. The discipline of risk analysis has developed into an organized body of knowledge and methods only within the past 20 years. The passage of federal laws to protect public health and the environment has generated rapid growth in risk analysis in numerous fields. Statements of risk need to be understood to be useful to the public and environmental managers. This guidebook provides a tool for understanding risk analysis. Chapters: overview of risk analysis; hazard identification; risk assessment; and risk communication.
This important text comprehensively examines each of the elements for which carcinogenicity has been established, providing detailed information on the carcinogenicity and toxicity and detailing the most up-to-date research in this area.
Comprehensive and international in content, Dietary anticarcinogens and antimutagens: Chemical and biological aspects includes topics as diverse as the health benefits of tea, wine and beer, through the prevention of various cancers, to the development of effective communication for healthy eating. The book is organised in to sections covering: epidemiology of diet and cancer; mechanisms of DNA damage and repair; the body's various protective mechanisms; and experimental approaches to the study of diet and cancer, with particular emphasis on humans as subjects.