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The Porphyrin Handbook, Volume 11: Bioinorganic and Bioorganic Chemistry presents the fundamental aspects of the synthesis, structure, chemistry, and spectroscopy of phthalocyanines. This book discusses the biology and medical implications of porphyrin systems. Organized into seven chapters, this volume begins with an overview of the design, synthesis, and study of the structural and functional models of heme/copper terminal oxidases. This text then examines the proteins containing iron-protoporphyrin IX (heme), which play key roles in photosynthesis and respiration. Other chapters consider the syntheses of chiral porphyrin derivatives and summarize the uses of such compounds in enantioselective control. This book discusses as well the reactivity and synthesis of synthetic carbine metalloporphyrins. The final chapter deals with the B12-coenzymes, which is the most complex and physiologically important organometallic enzymatic reactions that directly depend on the reactivity of metal coordinated organic ligands. This book is a valuable resource for research scientists, clinicians, and engineers.
As one of the oldest scientific institutions in the United States, the US Naval Observatory has a rich and colourful history. This volume is, first and foremost, a story of the relations between space, time and navigation, from the rise of the chronometer in the United States to the Global Positioning System of satellites, for which the Naval Observatory provides the time to a billionth of a second per day. It is a story of the history of technology, in the form of telescopes, lenses, detectors, calculators, clocks and computers over 170 years. It describes how one scientific institution under government and military patronage has contributed, through all the vagaries of history, to almost two centuries of unparalleled progress in astronomy. Sky and Ocean Joined will appeal to historians of science, technology, scientific institutions and American science, as well as astronomers, meteorologists and physicists.
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