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La Famiglia Moratti
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CROP Project
CROP Project: Deep Seismic Exploration of the Central Mediterranean and Italy presents and discusses new data ranging from Alps to Africa, obtained by the CROP PROJECT (transcrustal seismic exploration of the Mediterranean and Italy). New lithospheric imagings of relevant importance for understanding disputed topics are provided. Alps, Apennines, Calabrian Arc, Sicilian Apennine, Maghrebian Chain, Corso-Sardinian Block, paleo-basins (Ionian, Alpine Tethys), neo-basins (Balearic and Tyrrhenian) are innovatively reconstructed. Provides new data from the Alps to Africa Presents interpretation of the CROP seismic network data Offers a stepwise increase in information with new data for further studies
Tectonics of the Western Mediterranean and North Africa
This book provides an updated insight into the overall tectonic evolution of the Western Mediterranean region and North Africa. The tectonic setting of the region reflects a long-lived and complex evolution, mainly related to the Alpine Orogeny. This inheritance is expressed by an intricate pattern of arc-shaped mountain chains, the Alps, the Betic-Rif Cordilleras and the Apennine-Maghrebian belt, whose southern branches mark the present limit between the African and Eurasian plates. The volume covers the Maghrebian chains in North Africa, from Tunisia to Morocco and the Western and Central Mediterranean, from Spain to Italy from the pre-orogenic phases (Palaeozoic-Mesozoic) to the post-collisional neotectonic and Quaternary development. It includes both original research papers and syntheses dealing with the aspects of structural, sedimentary, metamorphic, marine geology.
Plasma Cell Dyscrasias
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
The Northern Adriatic Ecosystem
The northern Adriatic Sea is transient, most recently flooded between 18,000 to 6,000 years ago following the last glacial maximum, and it will drain again with the onset of the next glacial period. Despite its youth, uniformly shallow depth, and flat sediment floor, it hosts a broad range of bottom-dwelling sea life ecologically resembling communities that have existed in the shallow sea since the Ordovician Period, some 500 million years ago. The northern Adriatic is a natural laboratory in which to test hypotheses concerning the shift from the Paleozoic prevalence of stationary suspension-feeders living on the surface of the sediment and feeding from the overlying waters to, more recently...
Progress in Volcanology
Progress in Volcanology includes nine chapters in three sections. The first section is the “Introduction” while the other two sections speak on “Applied Volcanology” and “Volcanic Sedimentology, Geochemistry and Petrology.” The chapters address volcanology in several areas around the world, including Italy, Indonesia, Ethiopia, Argentina, India, and others.
Levodopa-Induced Dyskinesia in Parkinson's Disease
This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from ‘bench to bedside’. Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cellular, neurochemical, neurophysiological and circuitry level with detailed discussion of mechanisms and future directions to take the field forward; clinical studies from phase II to phase IV; on going RCTs in LID and evidence-based medicine reviews of treatment options. Levodopa-Induced Dyskinesia in Parkinson’s Disease is aimed at an international audience of movement disorder neurologists; neuroscientists; trainees and graduate and post-graduate students.
Amyloid and Amyloidosis
This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins, protein folding disorders, and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders, diagnosis, and treatments, incl
Multiple Myeloma
Multiple myeloma is a malignant disorder characterized by the proliferation of plasma cells. Much insight has been gained into the molecular pathways that lead to myeloma and indeed much more remains to be done. The understanding of these pathways is closely linked to their therapeutic implications and is stressed upon in the initial chapters. Recently, the introduction of newer agents such as bortezomib, lenalidomide, thalidomide, liposomal doxorubicin, etc. has led to a flurry of trials aimed at testing various combinations in order to improve survival. Higher response rates observed with these agents have led to their integration into induction therapies. The role of various new therapies vis a vis transplantation has also been examined. Recent advances in the management of plasmacytomas , renal dysfunction, dentistry as well as mobilization of stem cells in the context of myeloma have also found exclusive mention. Since brevity is the soul of wit our attempt has been to present before the reader a comprehensive yet brief text on this important subject.
