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Chromosomal Translocations and Oncogenic Transcription Factors
Regulation of gene expression at the level of transcription is one of the major determinants of proper cellular proliferation and differentiation. The key players in these processes are sequence-specific DNA binding transcription factor proteins which coordinate programs of gene expression in the nucleus. The articles in this volume document the myriad of genetic and biochemical alterations sustained by human proto-oncogenic transcription factors which result in diverse neoplastic processes. This volume gives insights into how normal programs of gene expression can be subverted by the action of single transcription factors resulting in a specific tumor type. The book provides inspiration for exploiting these tumor-specific alterations as diagnostic, prognostic tools, or as selective therapeutic targets.
Congressional Record
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
Journal of the House of Representatives of the United States
Some vols. include supplemental journals of "such proceedings of the sessions, as, during the time they were depending, were ordered to be kept secret, and respecting which the injunction of secrecy was afterwards taken off by the order of the House".
No Hill Too High for a Stepper
Born during the Great Depression, Mike Mahan was in many ways a very lucky boy. His parents, a barber and a beautician, owned their own shop and home, always providing ample food, clothing, and warmth. No Hill Too High for a Stepper is not, then, the usual story of economic or family struggle, but rather a celebration of life in Montevallo, Alabama, during the thirties, forties, and fifties. It paints excellent portraits of unusually supportive parents as well as of other family members and townspeople, creating a detailed sense of small-town life during this period. At the heart of this book is an absorbing depiction of an irrepressible child and adolescent who approached all of life with a great sense of wonder and who meant to live it to the fullest. Throughout the memoir, the reader comes to see the richness of this life and the pride with which Mahan remembers it.
Hearing in Children, Sixth Edition
In this completely updated sixth edition, Hearing in Children thoroughly examines the current knowledge of pediatric audiology, and provides a medical perspective on the identification, diagnosis, and management of hearing loss in children. This enduring text has been the chief pediatric hearing resource used worldwide by audiologists for nearly 40 years. Key features to Hearing in Children, Sixth Edition include: An expanded review of the medical aspects--early intervention, genetics, diseases and disorders, and treatments--of pediatric hearing loss as well as hearing and auditory disorders in infants, toddlers, and young childrenPractical descriptions of age-specific testing protocols and ...
Journals
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A Matter of Destiny
This is the story of a man who falls in love three weeks before leaving for flight training, tells of the different backgrounds of two people, the struggles of separation, and the Korean War · all of which seem insurmountable odds for this young couple. Written fresh and vibrant by a man whose been there, this novel puts you right in the cockpit right in the rice paddy, right in the lovers arms. Not only is this a love story but it is a study in human behavior, revealing the conflict between a mother and a son, a tumultuous new relationship, and the realism of a fighter pilot’s war. These are the forces that ultimately affect the destiny of two people.
Chicago Pre-Boomers
Many place self-interest above personal relationships, but Shawn Butler's priorities differ. He seeks to elevate people, not defeat them. When solving problems, Shawn collaborates rather than compete. In dealing with matters such as a fist fight or a Marine hitch, he strives to maintain his perspective. Later, Shawn enlists his supporters to help him cope with a senseless tragedy. As he assembles and trains teams, his nerdy best friend, Nick, analyzes situations. When these two men face high-stakes decisions, their friendship is threatened. Most people have a price. Will Shawn discover his?
