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Life in the Frozen State
While it is barely 50 years since the first reliable reports of the recovery of living cells frozen to cryogenic temperatures, there has been tremendous growth in the use of cryobiology in medicine, agriculture, horticulture, forestry, and the conservation of endangered or economically important species. As the first major text on cryobiolog
Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, 2 Volume Set
Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component...
Microbial Ecology of Leaves
The leaf surface or phyllosphere is a major habitat for microorganisms. Microbes on or within leaves play important roles in plant ecology, and these microbes can be manipulated to enhance plant growth or reduce plant disease. This book presents a number of critical reviews by internationally recognized experts on the microbial ecology of leaves. Topics include methods of assessment of microbial populations on leaf surfaces, leaves as reservoirs of ice nucleation phenomenon, and leaves as microbial habitats in both aquatic and terrestrial environments. The book will be of interest to students and scientists in numerous disciplines, including botany, aerobiology, meteorology, ecology, agriculture, and microbiology.
Alcamo's Microbes and Society
Revised and updated to reflected new information in the field, the Third Edition of Alcamo's Microbes and Society is intended for liberal arts students taking a foundation course in the life sciences. It discusses the role of microbes in our everyday lives, from food production to their roll in biotechnology and the numerous other ways that microbes contribute to our world. It goes on to explore such topics as the function of microbes in ecological systems and environmental systems. Coverage of bioterrorism, antibiotic resistance, and microbial disease offer students a broad and current perspective of the extensive impact of various microbes. Consistent with Edward Alcamo's student-friendly writing style, material is presented in a lively format that will engage students and highlight both the positive and negative impact that microorganisms have in our society.
Leading Topics in Cancer Research
Cancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures. This book brings together important research from around the world in this frontal field.
Recombinant Gene Expression
Since newly created beings are often perceived as either wholly good or bad, the genetic alteration of living cells impacts directly on a symbolic meaning deeply imbedded in every culture. During the earlier years of gene expression research, te- nological applications were confined mainly to academic and industrial laboratories, and were perceived as highly beneficial since molecules that were previously unable to be separated or synthesized became accessible as therapeutic agents. Such were the success stories of hormones, antibodies, and vaccines produced in the bacterium Escherichia coli. Originally this bacterium gained fame among humans for being an unwanted host in the intestine, or w...
Molecular Basis of Breast Cancer
This richly-illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The text is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.
Molecular Markers of Brain Tumor Cells
Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual i...
Evolutionary Trajectories in Plant-Associated Pseudomonas and Xanthomonas Strains
The strict relationships between bacteria and plants represents one of the major facets of terrestrial ecology. Depending on the type of interaction and amount of metabolic advantage one organism can obtain from such relationships, these are classified as mutualistic, commensal or parasitic interactions. Within this context, Pseudomonas and Xanthomonas are bacterial genera with a worldwide spread, capable of establishing all of the above mentioned interactions with plants. Therefore, they represent good models for studying different lifestyles and, accordingly, deciphering distinct evolutionary trajectories followed by different lineages of a single genus to infect and/or to establish a mutualistic relationships with the plant. Some members of these two genera are regulated pests that are recognized as economically major threats for their host crop(s) both in temperate and tropical environments.
Genomic and Personalized Medicine
Genomic and Personalized Medicine, Second Edition - winner of a 2013 Highly Commended BMA Medical Book Award for Medicine - is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medi...
