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In Situ Hybridisation
The editors of this book have brought together contributions from leaders in the application of "in situ" hybridization and guide the reader through the various options and variations of the technique.
Your Genes, Your Health
New advances in genetics have dramatically expanded our ability to avoid, prevent, diagnose, and treat a wide range of disorders. Now, more than ever, families need to know about these new discoveries, especially as there are some 7,000 rare genetic diseases that afflict about 1 in 12 of us. In Your Genes, Your Health, Aubrey Milunsky provides an invaluable and authoritative guide to what you should know about your genes. Illustrated with poignant family histories that underscore the lifesaving importance of knowing one's family medical history and ethnic origin, the book highlights the importance of recognizing seemingly unrelated disorders in a family as due to the same gene mutation and i...
High Plains Horticulture
High Plains Horticulture explores the significant, civilizing role that horticulture has played in the development of farmsteads and rural and urban communities on the High Plains portions of Colorado, Kansas, Nebraska, South Dakota, and Wyoming, drawing on both the science and the application of science practiced since 1840. Freeman explores early efforts to supplement native and imported foodstuffs, state and local encouragement to plant trees, the practice of horticulture at the Union Colony of Greeley, the pioneering activities of economic botanists Charles Bessey (in Nebraska) and Aven Nelson (in Wyoming), and the shift from food production to community beautification as the High Plains...
Advances in Developmental Biochemistry
Volume 3 of Advances in Developmental Biology and Biochemistry consists of five chapters that review specific aspects of mammalian and fly development. In Chapter 1, D. Chapman and D. Wolgemuth discuss the role of protein kinases, especially tyrosine-and serine/threonine kinases, in regulating cell cycle events during mammalian gametogenesis. IN Chapter 2, M. Lundell and J. Hirsh discuss the regulation of the DOPA decarboxylase gene during Drosophila development. DO PA decarboxylase is a key enzyme in biogenic amine biosynthesis and its expression is subject to both transcriptional and post-transcriptional regulation. In Chapter 3, S. Potter discusses the role of homeobox genes as master switches determining the developmental destinies of groups of cells during murine development. In Chapter 4, G. Cooper discusses the expression and function of the c-mos proto-oncogene in mammalian germ cells where it plays a central role in regulating the meiotic cell cycle. In Chapter 5, F. Beermann, R. Ganß, and G. Schütz discuss the regulation of pigmentation during mammalian development, with emphasis on the production of melanin in mouse melanocytes.
Microsurgical Models in Rats for Transplantation Research
Preclinical experimental transplantation research that is based on microsurgical models in rats fulfills two indispensable conditions for modern organ transplanta tion research: Almost all organ grafts can be performed on the rat with an amount of technical effort that is still justifiable. Thus transplantation models that are analogous to human organ transplantation can be developed, tested, and evaluated. This fulfills a necessary condition from the standpoint of surgery. With the species rat, we have a great variety of genetically different inbred strains. From the immunological point of view this is an indispensable prerequisite for the investigation of preclinical transplantation models...
The Selfish Gene
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Genomic Control Process
Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological re...
How to Commercialise Research in Biotechnology?
Biotechnology is considered as a key technology of the 21st century with the potential to offer technological solutions for global health and resource-based problems. Oliver Uecke analyses how early stages of the innovation process in biotechnology can be effectively managed, with the aim to transfer an innovation from academia to industry. A mixed method approach is applied with a multiple case study approach to identify characteristics for effective management and with the method of discrete choice experiments/best-worst scaling to estimate the importance of these characteristics. This study adds to existing research by identifying a group of five important characteristics that should be considered in the early stages of the innovation process, compared to a group of four characteristics that are less important. The results have implications for policy, directors and the management of research institutes and universities, entrepreneurs, TTO manager and other stakeholders involved in technology transfer.
