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"Advanced Tribology" is the proceedings of the 5th China International Symposium on Tribology (held every four years) and the 1st International Tribology Symposium of IFToMM, held in Beijing 24th-27th September 2008. It contains seven parts: lubrication; friction and wear; micro/nano-tribology; tribology of coatings, surface and interface; biotribology; tribo-chemistry; industry tribology. The book reflects the recent progress in the fields such as lubrication, friction and wear, coatings, and precision manufacture etc. in the world. The book is intended for researchers, engineers and graduate students in the field of tribology, lubrication, mechanical production and industrial design. The editors Jianbin Luo, Yonggang Meng, Tianmin Shao and Qian Zhao are all the professors at the State Key Lab of Tribology, Tsinghua University, Beijing.
This book focus on innovation, main objectives are to bring the community of researchers in the fields of mechanical design together; to exchange and discuss the most recent investigations, challenging problems and new trends; and to encourage the wider implementation of the advanced design technologies and tools in the world, particularly throughout China. The theme of 2021 ICMD is “Interdisciplinary and Design Innovation” and this conference is expected to provide an excellent forum for cross-fertilization of ideas so that more general, intelligent, robust and computationally economical mechanical design methods are created for multi-disciplinary applications.
Manufacturing industry has been one of the key drivers for recent rapid global economic development. Globalisation of manufacturing industries due to distributed design and labour advantage leads to a drive and thirst for technological advancements and expertise in the fields of advanced design and manufacturing. This development results in many economical benefits to and improvement of quality of life for many people all over the world. This rapid development also creates many opportunities and challenges for both industrialists and academics, as the design requirements and constraints have completely changed in this global design and manufacture environment. Consequently the way to design,...
Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manip...
The burgeoning field of nanotechnology has led to many recent technological innovations and discoveries. Understanding the impact of these technologies on business, science, and industry is an important first step in developing applications for a variety of settings and contexts. Handbook of Research on Nanoscience, Nanotechnology, and Advanced Materials presents a detailed analysis of current experimental and theoretical approaches surrounding nanomaterials science. With applications in fields such as biomedicine, renewable energy, and synthetic materials, the research in this book will provide experimentalists, professionals, students, and academics with an in-depth understanding of nanoscience and its impact on modern technology.
Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company, and a substantial number of biotechnology companies, targeting epigenetic processes to treat diseases ranging from cancer to Huntington’s disease and from inflammation to sickle cell anaemia. This book aims to provide an overview of the key topics adopted in current epigenetic drug discovery programmes with a focus on major developments and new technologies. Importantly, the book incorporates case studies and outlines the key challenges and techniques employed to overcome them. The book is an ideal resource for researchers in both industry and academia with an interest in epigenetic and genetic factors involved in drug discovery, target ID and validation. The book is also an excellent introduction for postgraduates interested in the interface between epigenetics and pharmaceuticals.
The 2nd Annual 2016 International Workshop on Materials Science and Engineering (IWMSE 2016) was held in Guangzhou, Guangdong, China on August 12 - August 14, 2016. The main aim of IWMSE 2016 was to provide a platform for scientists and engineers, to get together to share their research findings, exchange ideas and identify the future directions of R&D in materials science.In this conference, we have received over 272 high-quality papers, however, only 160 articles are included in the proceedings, covering topics such as ceramics and glasses, amorphous materials, nanomaterials and thin layers, soft magnetic materials, biomaterials, polymers, photovoltaic materials, steels, tool materials, composites, as well as functional and smart materials.