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Molecular Therapies of Cancer
  • Language: en
  • Pages: 488

Molecular Therapies of Cancer

  • Type: Book
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  • Published: 2015-07-22
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  • Publisher: Springer

Molecular Therapies of Cancer comprehensively covers the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is currently available a great deal of literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles superficially connected to one another. There is a lack of comprehensive and systematic text on the topic of molecular therapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal chemistry or signal transduction, rather than explaining molecular drug actions across all those areas; Molecular Therapies of Cancer fills this void. The book is divided into five sections: 1. Molecular Targeting of Cancer Cells; 2. Emerging and Alternative Treatment Modalities; 3. Molecular Targeting of Tumor-Host Interactions; 4. Anti-Cancer Drug Pharmacokinetics; and 5. Supportive Therapies.

How Complexity Shapes the World
  • Language: en
  • Pages: 370

How Complexity Shapes the World

This book explores how we may overcome categorizations and opposites in how we explain all existence. It places such ideas into the context of existing complexity paradigms. Research into complex systems has revolutionized virtually all areas of inquiry over the past half century. The algorithms of non-linear systems research have enabled us to unify descriptions of the world that were distinct under traditional, reductionist explorations. It is the beauty of complexity that it brings together various scientific fields that, in the past, were treated as separate entities under specialized study. They are now found to be governed by the same laws of non-linearity. However, this achievement comes at the price of abstraction and open-endedness. The book is motivated by the philosophical desire to eliminate categorizations and opposites in the sciences and arrive at a unified description of nature and society. To the reader, it offers innovative philosophical insights derived from complexity research.

Molecular Mechanisms of Cancer
  • Language: en
  • Pages: 643

Molecular Mechanisms of Cancer

This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumor-host interactions (with the endocrine system, the immune system, and blood vessel formation), and the underlying molecular defects of individual cancers.

Cancer Therapy
  • Language: en
  • Pages: 394

Cancer Therapy

Tumor-host interaction is critical for cancer proliferation and spread. Tumor mass, metastasis, invasion of host tissue, evasion of the host immune response, and tumor drug resistance are all affected by the interaction between the tumor cell and the host. Molecular strategies to interrupt the tumor-host interaction are among the most promising new leads to emerge in cancer pharmacogenomics and oncogenomics in recent years. This book critically reviews every aspect of this major topic in cancer research. In the opening chapter, Liang and colleagues describe the use of differential display to identify novel cancer-associated genes. This is followed by a chapter in which Aronow et al. describe...

Index of Patents Issued from the United States Patent and Trademark Office
  • Language: en
  • Pages: 1910

Index of Patents Issued from the United States Patent and Trademark Office

  • Type: Book
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  • Published: 1989
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  • Publisher: Unknown

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German Immigrants
  • Language: en
  • Pages: 200

German Immigrants

A partial reconstruction of Bremen passenger lists based on U.S. sources. Not all Bremen passengers are included; only those giving a specific place of origin in Germany. This is about 21%; those giving only "Germany" as place of origin was about 79%.

Index of Patents Issued from the United States Patent Office
  • Language: en
  • Pages: 2300

Index of Patents Issued from the United States Patent Office

  • Type: Book
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  • Published: 1975
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  • Publisher: Unknown

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Bayer. Zentral-Polizei-Blatt
  • Language: de
  • Pages: 554

Bayer. Zentral-Polizei-Blatt

  • Type: Book
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  • Published: 1885
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  • Publisher: Unknown

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Carl Maria von Weber
  • Language: en
  • Pages: 422

Carl Maria von Weber

The first edition of John Warrack's study of Weber was published in 1968 and quickly became recognized as the standard 'life and works' - indeed the best book on Weber in any language. The second edition was produced in 1976 to mark the 150th anniversary of Weber's death in London, and is reissued here. John Warrack's study gives a detailed account of the life in which the music is discussed (with analysis and music examples) in chronological order. It is a scholarly study based on first-hand research in German and other archives, but it is also elegantly written, and fully alive to general cultural and historical implications. It is a book for the music-lover as well as the scholar. This second edition contains a new concluding chapter, an important select bibliography of over 100 entries, and a useful family tree which was not in the first edition.

Passenger and Immigration Lists Index
  • Language: en
  • Pages: 904

Passenger and Immigration Lists Index

  • Type: Book
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  • Published: 2009
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  • Publisher: Unknown

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