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Toxicology and Risk Assessment
This new book, written by two outstanding scientists in the field, describes the basic principles of toxic mechanisms and organ toxicity, providing detailed information on specific mechanisms or chemicals for exemplification. The goal is to provide sufficient information that the reader becomes familiar with the basic concepts in toxicology to enable him or her to understand the basic principles in toxicology and to evaluate the risks at given exposures. With this basic understanding the reader also will be able to critically evaluate the available information on a chemical and to identify data gaps. In addition to the introductory chapters the book will offer the following systematic inform...
Transitioning to Sustainable Life below Water
The ocean plays a central role in the life and development of human kind. Besides space for navigation and trade (roughly 10 billion tons of commodities are transported across the oceans each year), the provision of biological and non-living resources is the most important service of the marine ecosystems. Yet, these ecosystems are increasingly impeded by human activities and interventions. Human and naturally induced changes in climate are buffered by the ocean, but its capacity to compensate the increase of CO2 in the atmosphere is at its limit. The increase of global temperatures and the decrease of oxygen concentration and pH are severe stressors for aquatic species and thus for the whol...
Nutrition and Integrative Medicine for Clinicians
Mystery illnesses can be helped, this book lays the groundwork for it. Building on its predecessor, this new volume, Nutrition and Integrative Medicine for Clinicians is an essential, peer-reviewed resource for practitioners, those in allied health care, and complementary/alternative medicine. The book contains valuable information for healthcare providers to use by helping patients manage, treat and even prevent illnesses and put them on a healthy path to recovery. This volume contains information on various subjects including: · Illnesses resulting from water damaged buildings and subsequent change in the microbiome of the building · Steps to heal from mold/mycotoxin illnesses · Effects...
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury
In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell proliferation and differentiation. Eicosanoids form a link between different fields of research into such areas as cancer, inflammation and radiation-induced injury. This link provided the impetus for the development of the conference series of which the present volume represents the proceedings of the Second International Conference, held in Berlin in October 1991.
Hormonal Carcinogenesis
In the past decade there has been a growing public interest and resurgence in research in the field of hormonal carcinogenesis. This is due to the widespread use of therapeutic hormonal agents worldwide and to the increasing awareness of the causal association of hormones, both endogenous and exogenously administered, and a variety of human cancers. These associations include estrogens in uterine, cervical, vaginal, liver, testicular, prostatic, and possible breast cancers; progesterone and progestational hormones in breast cancer; androgens and anabolic steroids in hepatic and prostatic cancers. Additionally, gonadotrophins playa role in the etiology of ovarian and testicular cancers and th...
