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Placebo and Pain
The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers' knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain:"This ambitious book is the first compreh...
Placebo
Due to the recent explosion of placebo research at many levels the Editors believe that a volume on Placebo would be a good addition to the Handbook of Experimental Pharmacology series. In particular, this volume will be built up on a meeting on Placebo which will be held in Tuebingen (Germany) in January 2013, and where the most prominent researchers in this field will present and exchange their ideas. The authors who will be invited to write chapters for this volume will be the very same speakers at this meeting, thus guaranteeing high standard and excellence in the topic that will be treated. The approach of the book is mainly pharmacological, including basic research and clinical trials, and the contents range from different medical conditions and systems, such as pain and the immune system, to different experimental approaches, like in vivo receptor binding and pharmacological/behavioral conditioning. Overall, the volume will give an idea of modern placebo research, of timely concepts in both experimental and clinical pharmacology, as well as of modern methods and tools in neuroscience.
Placebo and Pain
The magnitude of placebo analgesia effects has been shown to vary across meta-analyses. The conceptualization of placebo effects, and the way in which they are induced, influence the magnitude of placebo analgesia effects. This has been indicated by meta-analyses and further confirmed by experimental studies. In general, small placebo analgesia effects are found in clinical trials in which placebo is used as a control condition, whereas large effects are found in placebo mechanism studies investigating how expectations and emotional feelings contribute to placebo analgesia effects. At present, meta-analyses are used to investigate the seemingly increasing analgesic effects following placebo administration in clinical trials. Current knowledge about placebo mechanisms could contribute to the investigation of these analgesic effects and thereby help to develop new ways of testing pain medication, which ultimately may be of benefit for pain patients.
Investigating Pristine Inner Experience
You live your entire waking life immersed in your inner experiences (thoughts, feelings, sensations and so on) – private phenomena created by you, just for you, your own way. Despite their intimacy and ubiquity, you probably do not know the characteristics of your own inner phenomena; neither does psychology or consciousness science. Investigating Pristine Inner Experience explores how to apprehend inner experience in high fidelity. This book will transform your view of your own inner experience, awaken you to experiential differences between people and thereby reframe your thinking about psychology and consciousness science, which banned the study of inner experience for most of a century and yet continued to recognize its fundamental importance. The author, a pioneer in using beepers to explore inner experience, draws on his 35 years of studies to provide fascinating and provocative views of everyday inner experience and experience in bulimia, adolescence, the elderly, schizophrenia, Tourette's syndrome, virtuosity and more.
Quantitative Bioimaging
Quantitative bioimaging is a broad interdisciplinary field that exploits tools from biology, chemistry, optics, and statistical data analysis for the design and implementation of investigations of biological processes. Instead of adopting the traditional approach of focusing on just one of the component disciplines, this textbook provides a unique introduction to quantitative bioimaging that presents all of the disciplines in an integrated manner. The wide range of topics covered include basic concepts in molecular and cellular biology, relevant aspects of antibody technology, instrumentation and experimental design in fluorescence microscopy, introductory geometrical optics and diffraction ...
Placebo and Pain
Studies of placebo analgesia necessarily involve the induction and reporting of pain. The pain report is the basic dependent variable in many studies of placebo analgesia, and reported pain should ideally reflect the pain experience. However, the pain report is subject to a number of different influences that threaten the internal validity of research on pain and, consequently, placebo analgesia. The study of placebo analgesia introduces several other issues, in terms of the design of studies that researchers must deal with. Many methodologic issues have been solved, but some important issues are still unresolved. The concept of expectation is central to studies of placebo effects, and poses special challenges in terms of its conceptual status and its measurement.
Eurythmy Therapy
Created in 1911, eurythmy was developed for years as an artistic and educational discipline. Although Rudolf Steiner pointed out its healing aspects from the very beginning, it was only in 1921 that he gave a course of lectures that gave the art of eurythmy a vital new application. To the assembled eurythmists and doctors, he presented what one participant described as '...a complete and detailed method of eurythmy therapy, in which we could directly experience that even today the creative and therapeutic power of the word ... is still at work'.Steiner's comprehensive lectures, republished here in a thoroughly revised translation, describe the principles of therapeutic eurythmy, giving many ...
Pain 2012 Refresher Courses: 14th World Congress on Pain
Pain 2012: Refresher Courses, 14th World Congress on Pain, is based on IASP's refresher courses on pain research and treatment. Includes techniques (neuroimaging, genetics), treatments (interventional, psychological, pharmacological, complementary/alternative), and disorders (neuropathic pain, headache, cancer pain, musculoskeletal pain, CRPS, orofacial pain, postoperative pain, pediatric pain, abdominopelvic pain).
The Emperor's New Drugs
Everyone knows that antidepressant drugs are miracles of modern medicine. Professor Irving Kirsch knew this as well as anyone. But, as he discovered during his research, there is a problem with what everyone knows about antidepressant drugs. It isn't true. How did antidepressant drugs gain their reputation as a magic bullet for depression? And why has it taken so long for the story to become public? Answering these questions takes us to the point where the lines between clinical research and marketing disappear altogether. Using the Freedom of Information Act, Kirsch accessed clinical trials that were withheld, by drug companies, from the public and from the doctors who prescribe antidepress...
An Introduction To Graphene Plasmonics
This book is meant as an introduction to graphene plasmonics and aims at the advanced undergraduate and graduate students entering the field of plasmonics in graphene. In it different theoretical methods are introduced, starting with an elementary description of graphene plasmonics and evolving towards more advanced topics. This book is essentially self-contained and brings together a number of different topics about the field that are scattered in the vast literature. The text is composed of eleven chapters and of a set of detailed appendices. It can be read in two different ways: Reading only the chapters to get acquainted with the field of plasmonics in graphene or reading the chapters and studying the appendices to get a working knowledge of the topic. The study of the material in this book will bring the students to the forefront of the research in this field.
