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This book provides up-to-date information on some of the most important aspects of ryanodine receptor function and has been written by experts in the field. Included are reviews of the latest experimental data, critical assessments of the mechanisms of ryanodine receptor activation and regulation, and the role of the channel in controlling intracellular Ca2+ release.The approach to this subject is new. The book focuses on the biochemical and biophysical aspects of ryanodine receptor research, with particular emphasis on the single channel properties of reconstituted ryanodine receptors.
Drawing from the work of leading researchers in 26 countries, Biochemistry of Exercise X delivers an up-to-date, wide-ranging examination of membranes, muscles, and exercise. Experts in the field of biochemistry offer the latest research findings on topics such as signaling, excitation-contraction, metabolism, and adaption. The book features the proceedings of the prestigious Tenth International Conference on Biochemistry of Exercise held in Sydney, Australia, by the Research Group on Biochemistry of Exercise (ICSSPE) July 15-19, 1997. Featuring 48 illustrations and 9 tables, Biochemistry of Exercise X thoroughly examines recent findings on the basic mechanisms shaping exercise biochemistry and details their applications to specific areas in the field.
Embark on a captivating journey into the dynamic world of Muscle Physiology with our specialized guide. Tailored for students, researchers, and fitness enthusiasts, "Muscle Physiology" is a comprehensive book that unravels the intricacies of muscular systems. Enriched with in-depth insights, practical knowledge, and extensive Multiple-Choice Question (MCQ) practice, this guide is designed to deepen your understanding of muscle function, performance, and health. Key Features: Mechanisms of Muscle Contraction: Delve into the molecular and cellular processes that govern muscle contraction. "Muscle Physiology" provides a thorough exploration of the mechanisms, including the role of actin, myosin...
In recent years, the ryanodine receptor has emerged as a new and very promising target for the treatment of several cardiovascular disorders, including cardiac arrhythmias and heart failure. This volume is the most current publication devoted to the major intracellular calcium-release channel, the ryanodine receptor. "In this series of brief but informative chapters, the contributions progress from the basic gene family and primary structure, through its 3D structure so far, to its regulation and physiology." David E. Clapham, MD, PhD Professor of Neurobiology and Pediatrics Harvard Medical School Dr. Xander H.T. Wehrens received his M.D. and Ph.D. degrees from Maastricht University in the N...
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Winner of the Observer Food Monthly Cookbook of the Year 2013. Yotam Ottolenghi and Sami Tamimi are the men behind the bestselling Ottolenghi: The Cookbook. Their chain of restaurants is famous for its innovative flavours, stylish design and superb cooking. At the heart of Yotam and Sami's food is a shared home city: Jerusalem. Both were born there in the same year, Sami on the Arab east side and Yotam in the Jewish west. Nearly 30 years later they met in London, and discovered they shared a language, a history, and a love of great food. Jerusalem sets 100 of Yotam and Sami's inspired, accessible recipes within the cultural and religious melting pot of this diverse city. With culinary influe...
The incredible memoir from Lamb of God frontman, Randy Blythe. In 2010, a nineteen-year-old super-fan rushed the stage during a Lamb of God concert in Prague. To protect himself, singer Randy Blythe pushed the fan away. Unbeknownst to Blythe, the young man hit his head on the floor when he fell and later died from the injury. Blythe was promptly incarcerated on charges carrying a prison term of five to ten years. Thirty-seven days later, he was released on bail to await trial. Although legal experts told him not to return to the Czech Republic to face the charges, Blythe explained that he “could not run away from this problem while the grieving family of a dead young man searched hopelessly for answers that [he] might help provide.” After a five-day trial, he was acquitted on March 5, 2013. In Dark Days, Blythe tells the story of his incarceration and the wild life that led up to it. As he explains, “Most substance abuse books end with the author getting sober. My book starts there.”