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The modem microbiologist is often a real specialist who has difficulty under standing and applying many of the techniques beyond those in his or her own immediate field. On the other hand, most benefits to modem microbiology are obtained when a broad spectrum of scientific approaches can be focused on a problem. In early studies, electron microscopy was pivotal in understanding bacterial and viral morphology, and we still feel that we will understand a disease better if we have seen an electron micrograph of the causative agent. Today, because there is an increased awareness of the need to understand the rela tionships between microbial structure and function, the electron microscope is stil...
Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution...
This new edition of the universally acclaimed and widely-used textbook on fungal biology has been completely re-written, drawing directly on the authors' research and teaching experience. The text takes account of the rapid and exciting progress that has been made in the taxonomy, cell and molecular biology, biochemistry, pathology and ecology of the fungi. Features of taxonomic relevance are integrated with natural functions, including their relevance to human affairs. Special emphasis is placed on the biology and control of human and plant pathogens, providing a vital link between fundamental and applied mycology. The book is richly illustrated throughout with specially prepared drawings and photographs, based on living material. Illustrated life-cycles are provided, and technical terms are clearly explained. Extensive reference is made to recent literature and developments, and the emphasis throughout is on whole-organism biology from an integrated, multidisciplinary perspective.
Recent findings on the role of the cell wall of pathogenetic fungi in the pathogenic processes of both vertebrates and invertebrates are presented. The fungal cell wall not only gives shape to the fungus, but it is a dynamic structure allowing fungal growth and survival of fungi in both friendly and adverse environments. It acts as a living sieve controlling the entry of nutrients and the secretion of metabolic products. In terms of fungal pathogenesis, the fungal wall may be responsible for eliciting the defense response of their respective invertebrate or vertebrate hosts or conversely it may provide protection against the host defense system during the pathogenic process.
Leonard Sowerby's self-healing manual for women, TheLadies' Dispensatory, emerged in England in 1652 amidst an abundance of medical self-help books for the lay citizen. Written for both the common patient and the amateur health provider, these manuals of home remedies provided their readers with a variety of potential solutions to common ailments or disease. Sowerby's Dispensatory was written primarily for curing women's health problems, and in that regard, focuses heavily on gynecologic problems (the Dispensatory includes numerous preparations for inducing abortion), breast complaints, personal hygiene and cosmetic applications. Balaban, Erlen and Siderits have resurrected Sowerby's original manuscript and have provided both historical and medical explanation of its uses and usefulness. From a common garlic remedy to 'fortify the brain' to 'a hog's heel, burned to powder' for easing colic, The Ladies' Dispensatory is a delightfully unique look at health and hygiene in the seventeenth century. Also inlcludes nine maps.
With the development of highly sophisticated analytical techniques and instrumentation during the past 15-20 years, progress in the field of lipid biochemistry has been greatly accelerated. Within this period, there has been an increasing volume of information concerning the distribution and metabolism of lipids in animals and, more recently, in plants. The fungi have played an important role in studies concerning the biochemistry of lipids and, in this text, they are treated separately from the photosynthetic plants. This book is concerned with distribution and bio chemistry of lipids in fungi. The text is divided into three sections, beginning with an introduction to fungallipids which inc...
Fungal dimorphism is a topic that sounds inherently too rarified to attract more than a specialist audience. Yet some 230 individuals representing an eclectic mixture of interests, from basic science to medical practice, gathered in Churchill College, Cambridge in Semptember 1992 for a meeting devoted only to this subject. The symposium was the fourth in a series "Topics in Mycology" to be jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology. The participants enjoyed a rich and varied diet of oral presentations and poster displays in the field of fungal morphogenesis. This book sets down in print the material presented at the dimorp...