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Transitioning to Good Health and Well-Being
Transitioning to Good Health and Well-Being addresses critical issues of health in the context of sustainability, which need to be tackled in order to achieve Agenda 2030. Acknowledging the dramatic improvements that have been made in the past decades with regards to health, we also face disparities that remain amongst and within countries. While life expectancy has more than doubled, we are, at the same time, confronted with the challenges that come along with population growth alongside environmental change, migration, ageing, and economic disparities. In its 2018 progress report concerning SDG 3, the UN stated that, while the quality of global health is increasing, “people are still suf...
Steroid Enzymes and Cancer, Volume 1155
The expression and activity of key enzymes of sex steroid metabolism have major implications in both development and progression of various human hormone-related tumors, including breast, prostate, lung, and liver cancer. This volume explores the role of local synthesis of steroid hormones, a process that has assumed an increasing importance in our understanding about several malignancies originating from steroid target tissues, wherein abnormal levels of individual steroids may promote tumor growth. In this framework, a divergent expression and/or activity of key gonadal steroid enzymes (including dehydrogenases, hydroxylases, sulfotransferases, sulfatases, and aromatase) may eventually lea...
Prostate Cancer: A Comprehensive Perspective
Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.
Development of voluntary guidelines for the sustainability of the Mediterranean diet in the Mediterranean region
The Mediterranean diet is attracting international attention as a healthy and sustainable diet, yet countries in the region are increasingly beset by problems of undernutrition combined with obesity or other food-related diseases. This book highlights the need to consolidate the Mediterranean diet as a lever to improve the sustainability of food systems and consumption in the region.
Cancer Research
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Molecular Markers and Targeted Therapy for Hepatobiliary Tumors, volume I.A
Hepatobiliary tumor, mainly including hepatocellular carcinoma, cholangiocarcinoma and gallbladder cancer, is a group of highly aggressive malignancies. Hepatocellular carcinoma, cholangiocarcinoma and gallbladder cancer have different biological characters, histopathological traits, and treatment strategies, but have similar clinical features such as silent early symptom and extremely poor prognosis. The diagnostic, predictive or prognostic tumor biomarkers of hepatobiliary cancers are in unmet need. In contrast to the poor outcome, the treatment options to hepatobiliary cancers are very limited. It is still controversial about the effects of chemotherapy and radiotherapy of hepatobiliary c...
Non-Reproductive Actions of Sex Steroids
Prominent clinicians and researchers from diverse disciplines discuss the basic cell and molecular biology of steroid action and sex steroids' effects on the nervous and immune systems. Provides an integrated evaluation of the advantages and disadvantages of hormone replacement therapy.
Basis for Cancer Management
This volume investigates the area of steroid actions in hormone-dependent cancer. Subjects covered: include molecular biology of steroid expression; oncogenes and tumour suppressor genes; steroid content and metabolism in breast tumours; regulation of cancer cell growth by hormones and anti-hormones; stromal-epithelial interactions in vitro; endocrine-related tumours (breast and prostate cancer); new specific enzyme inhibitors in the management of human cancer; mechanism of action of pure anti-hormones; selected oncogene products in cancer prognosis; clinical trials of breast and prostate cancer; and diet prevention and chemoprevention of main human tumours.
Hormone-related Tumors
The papers in this volume cover the biology and biochemistry of normal and cancer cell growth exhibited in a range of cancers including liver cancer, colorectal cancer, breast cancer, prostate cancer and leukaemia. Studies include the epidermilogy, risk factors and the natural histories of these cancers. Additional chapters examine different treatment modalities for various cancers.
