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A current review of basic research on Rickettsiales biology and pathogenesis in one comprehensive volume. • Details the scientific knowledge about how these obligate intracellular bacteria invade, survive and replicate inside eukaryotic cells. • Describes the spectrum of disease caused by an infection and the role of vectors in transmission. • Discusses protective and pathologic immune responses and establishment of persistent infection. • Describes the latest developments including genomics and progress in vaccine development. • Serves as a significant research book for scientists, physicians, medical students, public health professionals, epidemiologists, biocomputational scientists and government policy makers.
For many of us, these simple rewards are suf The purpose of this briefforeword is unchanged from the first edition; it is simply to make you, ficiently gratifying so that we have chosen to the reader, hungry for the scientific feast that spend our scientific lives studying these unusual follows. These four volumes on the prokaryotes creatures. In these endeavors many of the strat offer an expanded scientific menu that displays egies and tools as well as much of the philos the biochemical depth and remarkable physi ophy may be traced to the Delft School, passed ological and morphological diversity of prokar on to us by our teachers, Martinus Beijerinck, yote life. The size ofthe volumes might...
A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.