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Essentials of Experimental Surgery
This book covers all aspects of experimental gastrointestinal research including anatomy, physiology, surgical procedures and animal experimental models As well as being a useful reference guide to established scientists, it serves as an ideal introduction to the field of gastroenterology By consulting the book, the appropriate animal species and experimental model can be chosen for physiological and pathophysiological studies
Good News - Bad News: The Two Faces of Immune Privilege
Immune privilege was once thought to be the property of a few select sites that include the eye, brain, testis, pregnant uterus and (of all things) the hamster cheek pouch, and was believed to be mainly based on sequestration behind blood-tissue barriers. This view has changed. Immune privilege is now considered to constitute a more general phenomenon through which tissues are able to actively direct and control immune responses taking place in their “territory” to preserve their structural and functional integrity in the face of inflammatory processes. These positive aspects of immune privilege can be hijacked by tumors to their survival advantage and to the detriment of the host. This Research Topic dissects the beneficial and deleterious consequences of immune privilege in terms of the cellular and molecular mechanisms that various tissues and tumors use, each in its own fashion, to regulate immune processes that affect them, at the local and the systemic level.
The Boston Directory
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Multidrug Resistance-associated Proteins
Organisms are said to be drug-resistant when drugs meant to neutralise them have reduced effect. When an organism is resistant to more than one drug, it is said to be multi-drug resistant. The most prominent example of this is antibiotic resistance. Drug resistance is also found in some tumour cells, which makes it more difficult to use chemotherapy to attack tumours made of those cells. When a drug such as an antibiotic is administered, those which have a genetic resistance to the drug will survive and reproduce, and the new population will be drug-resistant. This book provides in depth research on multi-drug resistance and its impact on neuorology. This includes studies on GS-X Pump/Multidrug Resistance Proteins, Quantitation of O6 -- Methylguanine, Therapeutic Responses to Chemotherapy, Profiles in Cancer, Neurodegenerative Diseases and Multiple Sclerosis.
Darwinism and the Divine
Darwinism and the Divine examines the implications of evolutionary thought for natural theology, from the time of publication of Darwin's On the Origin of Species to current debates on creationism and intelligent design. Questions whether Darwin's theory of natural selection really shook our fundamental beliefs, or whether they served to transform and illuminate our views on the origins and meaning of life Identifies the forms of natural theology that emerged in 19th-century England and how they were affected by Darwinism The most detailed study yet of the intellectual background to William Paley's famous and influential approach to natural theology, set out in 1802 Brings together material ...
Strategic Management
Strategic Management delivers an insightful, clear, concise introduction to strategy management concepts and links these concepts to the skills and knowledge students need to be successful in the professional world. Written in an accessible Harvard Business Review style with lots of practical examples and strategy tools, the book engages students with an easy-to-understand learning experience to strategic management concepts. This International Adaptation sparks ideas, fuels creative thinking and discussion, while engaging students via contemporary examples, outstanding author-produced cases, and much more. Every chapter now includes new questions to help readers test their understanding of the subject. There are also new Mini-Cases and Strategy in Practice vignettes that are contemporary and more relevant to the global scenario.
