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This book, the result of studies undertaken on behalf of the European Commission, examines the current 'state of the art' techniques for the restoration of despoiled lands arising from the coal and steel industries. It provides technical guidance to aid the process of the regeneration of the coal and steel communities of Europe. The chapters are fully cross referenced in the text, and where more technical or specific detail is provided, this has been placed into boxes rather than in the main text.The book will be of great interest to environmental scientists and engineers, and to all those who are involved in mining, mineral waste, soil pollution and waste management and disposal.
The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued un resol...
This volume contains the proceedings of the third in a series of conferences entitled, The International Symposium on Biological Reactive Intermediates. The first was held at the University of Turku in Finland, in 1975, the second at the University of Surrey in the United Kingdom, in 1980 and the most recent at the University of Maryland in the United States, in 1985. The significance of these conferences has been emphasized by the rapid growth of mechanistic toxicology over the last decade. These conferences were initially stimulated by the attempt to uncover the significance behind the observations that the toxicity of carcinogenic responses produced by many chemicals was associated with t...
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Having no competitive works, this unique publication presents a single structure for the analysis, explanation and solution of environmental problems, regardless of their location, nature or scale.In this problem-oriented approach, a coherent framework interconnects the study of facts and values, environmental systems, social causes and ethical premises. Counterbalancing current biases, the author emphasizes the fundamental, normative, economic and social-scientific aspects of truly interdisciplinary environmental science. For instance, the normative side of environmental problems are often neglected, resulting in policy designs and evaluations containing inefficient mixtures of sophisticate...
The first oral contraceptive became available in 1960 and since then these sub stances, which have been used by millions of women, have probably been the most widely studied group of drugs in medical history (Drill, 1966, 1977). Part of the evaluation oCoral contraceptives has involved their effect on the reproductive organs of women, with particular attention directed to evaluation of a possible carcinogenic effect of these steroids. To the extent that cancer of the reproductive organs is a common finding in women, the endogenous female sex hormones have been implicated in the occur rence of the cancer. The administration of estrogen has also been reported to in crease the incidence of cancer of the breast, cervix or endometrium in some strains or species of animals. Thus, because of the possible tumorigenic effect of estrogens there has been considerable interest in the relationship of oral contraceptives to cancer of the breast and genital tract.