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科学技术部国家重点基础研究发展规划项目,科学技术部基础性工作专项资助项目,国家自然科学基金会重点项目,中国科学院知识创新工程信息化建设专项课题,中国科学院南京地质古持物研究所创新基金。
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The multi-volume set LNAI 12975 until 12979 constitutes the refereed proceedings of the European Conference on Machine Learning and Knowledge Discovery in Databases, ECML PKDD 2021, which was held during September 13-17, 2021. The conference was originally planned to take place in Bilbao, Spain, but changed to an online event due to the COVID-19 pandemic. The 210 full papers presented in these proceedings were carefully reviewed and selected from a total of 869 submissions. The volumes are organized in topical sections as follows: Research Track: Part I: Online learning; reinforcement learning; time series, streams, and sequence models; transfer and multi-task learning; semi-supervised and f...
This new volume presents a selection of state-of-the-art technological advancements in IoT, network technologies, and software engineering that address unsolved issues in computational intelligence. The volume focuses on empirical, theoretical, and application perspectives on smart technologies and computational intelligence, identifying the advantages and limitations of each. The chapters on smart technologies address their application in communication services, healthcare and assistive technology, urban waste management, vehicle pollution and accident detection, and more. The technologies encompass the use of machine learning, blockchain, fog computing, etc. The volume goes on to discuss c...
Cancer is fundamentally a disease of abnormal cell proliferation: Cancer cells multiply when and where they should not. This proliferation entails escape from normal bounds imposed by the tissue environment, the internal biology of the cell (DNA damage, chromosomal imbalances, disorganized mitotic spindles), and the proliferative history of the cell (normal generational times). Some of the key oncogenic events in cancer directly perturb proteins that regulate progression through the cell division cycle, others alter cell cycle progression indirectly, through effects on signaling pathway that impinge on the cell cycle. This biology is fundamentally important in cancer therapy. Many of the workhorse treatments for cancer rely on killing proliferating cells. Furthermore, there is growing recognition that stem cell-transit amplifying cell hierarchies may persist or be generated during tumorigenesis, generating important functional heterogeneity in cell cycle control among tumor cells, with far-reaching scientific and clinical implications. This volume outlines major cell cycle perturbations that drive tumorigenesis and considers the prospects for using such knowledge in cancer therapy.
This is the first complete study of China's most popular eighteenth-century poet in any Western language. The work consists of a detailed biography, a study of Yuan's revolutionary reinterpretation of Chinese literary theory, and an analysis of his many contributions to the more original genres of Qing-dynasty (1644-1911) poetry such as narrative, historical, didactic, eccentric, and nature verse. The study is concluded by a generous and representative sampling of Yuan's poetry in translation, the first to do justice to the wide variety and richness of his oeuvre. Although many shorter poems are selected, this is the first translation to include his outstanding longer poetry. Harmony Garden will completely revise current attitudes in the west concerning classical Chines literature during the eighteenth century, a period that was long viewed as one of decline, but now appears to equal the golden ages of antiquity.
This book provides an accessible overview of each director’s contribution to cinema, incorporating a discussion of their career, major works and impact.