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The motivation for us to conceive this work on regulation was mainly our belief that it would be fun, and at the same time productive, to approach the subject in a way that differs from that of other treatises. We thought it might be interesting and instructive-for both author and reader-to examine a particular area of investigation in a framework of many different problems. Cutting across the traditional boundaries that have separated the sub jects in past volumes on regulation is not an easy thing to do-not because it is difficult to think of what interesting topics should replace the old ones, but because it is difficult to find authors who are willing to write about areas outside those p...
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This comprehensive yet balanced work emphasizes the principles and rationale underlying recombinant DNA methodology while furnishing a general understanding of the experimental protocols-suggesting flexible approaches to resolving particular molecular necessities that are easily adaptable to readers' specific applications. Features summary tables presenting at-a-glance information on practices of recombinant DNA methodologies! Recombinant DNA Principles and Methodologies discusses basic and advanced topics requisite to the employment of recombinant DNA technology, such as plasmid biology nucleic acid biochemistry restriction enzymes cloning strategies gel electrophoresis southern and norther...
Viral Genome Packaging focuses on the process of genome "packaging" within a pre-formed viral procapsid. The chapters of this book concentrate on the biochemistry, enzymology and structural aspects of the genome packaging machinery. This book defines a broad mechanistic basis for the process across the prokaryotic and eukaryotic border, and for DNA and RNA viruses. The biochemical, biophysical and structural aspects of genome packaging are examined in detail.
The University of Toronto’s Faculty of Medicine is North America’s largest medical school and a major health consortium, boasting nine affiliated teaching hospitals and a network of research institutes. It is where insulin was pioneered, stem cells were first discovered, and famous physicians from Vincent Lam to Sheela Basrur began their careers. But despite all its major accomplishments, the faculty’s impressive history has never before been comprehensively documented. In Partnership for Excellence, senior medical historian and award-winning author Edward Shorter details the Faculty of Medicine’s history from its inception as a small provincial school to its present day status as an international powerhouse. Deeply researched through front-line interviews and primary sources, it ties the story of the faculty and its teaching hospitals to the general history of medicine over this period. Shorter emphasizes the enormous concentration of intellectual energy in the faculty that has allowed it to become the dominant force in Canadian medicine, home to a legion of medical pioneers and achievements.
Un trozo de vestido de mujer arrojado por las olas del mar a una playa despierta la curiosidad de los detectives Raquenay Romero, quienes se sumergen en una trama que los lleva a involucrarse en el oscuro mundo de las finanzas de grandes corporaciones y en el de la industria manufacturera de celulosa y papel. La intriga, magistralmente narrada, se recorta además sobre un paisaje reconocible e identificable: el río Mataquito, el valle central de Chile.
Chile desorientado de Helios Murialdo Laport está integrado por comentarios, artículos y cartas enviadas a los diarios —algunas publicadas, otras inéditas— sobre la contingencia chilena de los últimos cinco años. Su visión, siempre lúcida y documentada, abrirá los ojos de los lectores sobre aspectos trascendentes del acontecer nacional que suelen pasarnos inadvertidos. Murialdo es autor de ocho novelas de género negro e innumerables artículos científicos publicados en revistas de todo el mundo. Vive parte del año en Chile, su país natal, y parte en Canadá, por lo que tiene una visión tanto interna como externa de los chilenos. Esto le permite otorgar un valioso punto de vista comparativo del acontecer local con una nación del primer mundo.
An absorbing portrait of the pioneering molecular biologist best known for demonstrating that DNA is the genetic component of phages, through essays and reminiscences from twenty–three distinguished scientists whose work and careers were influenced by the man and his science.