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Contemporary Challenges in Immunologic Testing in Clinical and Research Laboratories
Along the last several decades, it has been progressively appreciated that immunology plays an overwhelming role in the physiology and pathophysiology of most organs, tissues, and biological systems in multicellular organisms. Accordingly, several immunological parameters are used in research and clinical laboratories with the purpose of investigating, diagnosing, and monitoring a variety of pathological conditions. The rapidly evolving field of laboratory testing in immunology poses several challenges to professionals working in research and clinical laboratories, medical practice, educational activities, in vitro diagnostic industry, and regulatory agencies. Regular analytes, such as album...
The Complement System
As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Indeed, complement became a term that almost defies categorization. What was for a long time a subject for a limited number of specialists has now moved into the mainstream of experimental and clinical immunology. In 1973 I visited the Basel Institute of Immunology and met its director, the eminent scientist and Nobel laureate Nils Jerne. When I entered his office he greeted me with the following word...
The Norwegian Nominal System
This study presents a unified, economic account of the intricate relationship between form, meaning and interpretation in the Norwegian nominal system – without reference to polysemy. It covers all kinds of nominal signs, i.e. nouns, adjectives, pronouns and determiners, as well as the conventionalised syntactic combinations between them. Among its central innovations is the introduction of the feature general number into Norwegian morphology.
Adverbs and Adverbial Adjuncts at the Interfaces
This book clarifies - on the basis of mainly Hungarian data - basic issues concerning the category ‘adverb,’ the function ‘adverbial,’ and the grammar of adverbial modification. It argues for the PP analysis of adverbials, and claims that they enter the derivation via left- and right-adjunction. Their merge-in position is determined by the interplay of syntactic, semantic, and prosodic factors. The semantically motivated constraints discussed also include a type restriction affecting adverbials semantically incorporated into the verbal predicate, an obligatory focus position for scalar adverbs representing negative values of bidirectional scales, cooccurrence restrictions between ver...
Reference and Anaphoric Relations
This book is a collection of original research articles on the representation and in terpretation of indefinite and definite noun phrases, anaphoric pronouns, and closely related issues such as reference, scope and quantifier movement. A variety of frame works for the formal analysis of discourse semantics are represented, including dis course representation theory, file change semantics, dynamic Logic, E-type theories, and choice function approaches, which was one of the main issues the Konstanz project were concerned with. All of these frameworks are couched in the tradition of Montague Grammar, even though they extend the classical formalism in different directions. The developments emerg...
Formal Approaches to Languages of South America
This book analyzes the linguistic diversity of South America based on approaches deeply rooted in the tradition of formal grammar. The chapters brought together in this contributed volume consider native languages all kinds of languages used in the region, including sign languages, indigenous languages and the romance languages (Portuguese and Spanish) originally introduced by European colonizers which underwent processes of transformation giving rise to new, local grammars. One fourth of the language families of the world are located in South America, but the majority of languages in the region are still understudied and out of the radar of theoretical linguistics mostly because their gramm...
