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Systems Biology
This book explores Systems Biology as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. A variety of approaches are discussed here: the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close concert with experiment.
Genome Informatics 2008
This volume contains 25 peer-reviewed papers based on the presentations at the 8th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2008) held at the Teikyo Hotel, Zeuten Lake, near Berlin, from June 9 to June 10, 2008. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs and partner institutions: • Boston (Gary Benson) — Graduate Program in Bioinformatics, Boston University • Berlin (Herman-Georg Holzhütter) — The International Research Training Group (IRTG) “Genomics and Systems Biology of Molecular Networks” • Kyoto/Tokyo (Minoru Kanehisa/Satoru Miyano) — Joint Bioinformatics Education Program of Kyoto University and University of Tokyo.
Genome Informatics 2007: Genome Informatics Series Vol. 18 - Proceedings Of The 7th Annual International Workshop On Bioinformatics And Systems Biology (Ibsb 2007)
This volume contains 31 peer-reviewed papers based on the presentations at the 7th International Annual Workshop on Bioinformatics and Systems Biology (IBSB 2007) held at the Human Genome Center, Institute of Medical Science, University of Tokyo from July 31 to August 2, 2007. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs and partner institutions:• Boston (Charles DeLisi) — Graduate Program in Bioinformatics, Boston University• Berlin (Herman-Georg Holzhütter) — The International Research Training Group (IRTG) “Genomics and Systems Biology of Molecular Networks”• Kyoto/Tokyo (Minoru Kanehisa/Satoru Miyano) — Joint Bioinformatics Education Program of Kyoto University and University of Tokyo.This volume is dedicated to the memory of Prof. Dr. Dr. h.c. Reinhart Heinrich, a former Professor at Humboldt University Berlin and a co-founder of this workshop./a
Genome Informatics 2008: Genome Informatics Series Vol. 20 - Proceedings Of The 8th International Workshop On Bioinformatics And Systems Biology (Ibsb 2008)
This volume contains 25 peer-reviewed papers based on the presentations at the 8th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2008) held at the Teikyo Hotel, Zeuten Lake, near Berlin, from June 9 to June 10, 2008. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs and partner institutions:• Boston (Gary Benson) — Graduate Program in Bioinformatics, Boston University• Berlin (Herman-Georg Holzhütter) — The International Research Training Group (IRTG) “Genomics and Systems Biology of Molecular Networks”• Kyoto/Tokyo (Minoru Kanehisa/Satoru Miyano) — Joint Bioinformatics Education Program of Kyoto University and University of Tokyo.
Thermodynamics of Biochemical Reactions
Ein Lehr- und Handbuch der Thermodynamik biochemischer Reaktionen mit modernen Beispielen und umfangreichen Hinweisen auf die Originalliteratur. - Schwerpunkt liegt auf Stoffwechsel und enzymkatalysierten Reaktionen - Grundlagen der Thermodynamik (z. B. chemisches Gleichgewicht) werden anschaulich abgehandelt - zu den speziellen Themen gehören Reaktionen in Matrices, Komplexbildungsgleichgewichte und Ligandenbindung, Phasengleichgewichte, Redoxreaktionen, Kalorimetrie
Computational Science and Its Applications – ICCSA 2019
The six volumes LNCS 11619-11624 constitute the refereed proceedings of the 19th International Conference on Computational Science and Its Applications, ICCSA 2019, held in Saint Petersburg, Russia, in July 2019. The 64 full papers, 10 short papers and 259 workshop papers presented were carefully reviewed and selected form numerous submissions. The 64 full papers are organized in the following five general tracks: computational methods, algorithms and scientific applications; high performance computing and networks; geometric modeling, graphics and visualization; advanced and emerging applications; and information systems and technologies. The 259 workshop papers were presented at 33 workshops in various areas of computational sciences, ranging from computational science technologies to specific areas of computational sciences, such as software engineering, security, artificial intelligence and blockchain technologies.
MHC Ligands and Peptide Motifs
This book is centered on a comprehensive list of MHC peptide motifs and ligands as known to date, together with selected T cell epitopes, arranged in an easy-to-read fashion. This information is put into context by chapters on MHC gene organization, MHC structure, T cell epitope prediction, antigen processing and T cell responses. In addition, the book provides a great deal of complementary information: amino acid sequences of MHC class I alpha1 and alpha2 domains and of class II alpha1 and beta1 domains, the established or predicted composition and specificity of MHC pockets, notes on MHC nomenclature including old assignments and reference to useful internet addresses. A handy reference manual that should be helpful for all those dealing with MHC-associated peptides.
Systems Biology of Metabolic and Signaling Networks
Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comp...
Function and Regulation of Cellular Systems
Current biological research demands the extensive use of sophisticated mathematical methods and computer-aided analysis of experiments and data. This highly interdisciplinary volume focuses on structural, dynamical and functional aspects of cellular systems and presents corresponding experiments and mathematical models. The book may serve as an introduction for biologists, mathematicians and physicists to key questions in cellular systems which can be studied with mathematical models. Recent model approaches are presented with applications in cellular metabolism, intra- and intercellular signaling, cellular mechanics, network dynamics and pattern formation. In addition, applied issues such as tumor cell growth, dynamics of the immune system and biotechnology are included.
