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Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges.
Coeliac Disease (CD) affects at least 1% of the population. “Classical” CD refers to gastrointestinal presentations with anaemia and gastrointestinal symptoms. CD can, however, present with extraintestinal manifestations, the commonest of which are dermatitis herpetiformis and neurological presentations (e.g., ataxia, neuropathy, encephalopathy). Recognition and research into the pathophysiology of such manifestations is likely to enhance our understanding of this complex autoimmune disorder.
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye and barley) in genetically susceptible individuals. CD can manifest itself with a previously unappreciated range of clinical presentations, including the typical malabsorption syndrome and a spectrum of symptoms potentially affecting any organ system. Since CD often presents in an atypical or even silent manner, many cases remain undiagnosed and carry the risk of long-term complications, including anemia and other hematological complications, osteoporosis, neurological complications or cancer. The high prevalence of the disease and its variety of clinical outcomes raise several interesting questions. This book covers most of the aforementioned controversial and yet unresolved topics by including the contributions of experts in CD.What the reader will surely find stimulating about this book is not only its exhaustive coverage of our current knowledge of CD, but also provocative new concepts in disease pathogenesis and treatment.
Se ha preguntado alguna vez… • ¿Qué papel desempeñan los cuidadores en la atención a los pacientes de Alzheimer? • Si influye la genética en la enfermedad de Alzheimer. • ¿Cómo diferenciar la pérdida de memoria al inicio de la enfermedad de los olvidos habituales de las personas mayores? • Si existe prevención para la enfermedad de Alzheimer. • ¿Cómo evitar la pérdida de peso y apetito en los pacientes de Alzheimer? • Si protegen el café y otras bebidas con cafeína frente al Alzheimer. • ¿Dónde estará mejor el paciente con Alzheimer, en su hogar o en una residencia geriátrica? En formato pregunta-respuesta, por fin a su alcance y de la mano de dos especialistas, todas las claves sobre la enfermedad de Alzheimer. Una guía práctica que resuelve de manera definitiva y veraz sus dudas sobre diagnóstico y tratamiento, prevención, alimentación, estilo de vida y la forma de tratar trastornos de conducta alimentaria durante la enfermedad.
Recursos humanos en investigación y desarrollo.--V.2.
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