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The formulation, analysis, and re-evaluation of mathematical models in population biology has become a valuable source of insight to mathematicians and biologists alike. This book presents an overview and selected sample of these results and ideas, organized by biological theme rather than mathematical concept, with an emphasis on helping the reader develop appropriate modeling skills through use of well-chosen and varied examples. Part I starts with unstructured single species population models, particularly in the framework of continuous time models, then adding the most rudimentary stage structure with variable stage duration. The theme of stage structure in an age-dependent context is de...
Providing a self-contained treatment of persistence theory that is accessible to graduate students, this monograph includes chapters on infinite-dimensional examples including an SI epidemic model with variable infectivity, microbial growth in a tubular bioreactor, and an age-structured model of cells growing in a chemostat.
The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.
This book is an outcome of the Second International Conference on Mathematical Population Dynamics. It is intended for mathematicians, statisticians, biologists, and medical researchers who are interested in recent advances in analyzing changes in populations of genes, cells, and tumors.
This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of ? along with many new ideas and results on ? infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.
Informally, $K$-theory is a tool for probing the structure of a mathematical object such as a ring or a topological space in terms of suitably parameterized vector spaces and producing important intrinsic invariants which are useful in the study of algebr
This IMA Volume in Mathematics and its Applications MATHEMATICAL APPROACHES FOR EMERGING AND REEMERGING INFECTIOUS DISEASES: MODELS, AND THEORY METHODS is based on the proceedings of a successful one week workshop. The pro ceedings of the two-day tutorial which preceded the workshop "Introduction to Epidemiology and Immunology" appears as IMA Volume 125: Math ematical Approaches for Emerging and Reemerging Infectious Diseases: An Introduction. The tutorial and the workshop are integral parts of the September 1998 to June 1999 IMA program on "MATHEMATICS IN BI OLOGY. " I would like to thank Carlos Castillo-Chavez (Director of the Math ematical and Theoretical Biology Institute and a member of...
This textbook provides a comprehensive introduction to the qualitative theory of ordinary differential equations. It includes a discussion of the existence and uniqueness of solutions, phase portraits, linear equations, stability theory, hyperbolicity and equations in the plane. The emphasis is primarily on results and methods that allow one to analyze qualitative properties of the solutions without solving the equations explicitly. The text includes numerous examples that illustrate in detail the new concepts and results as well as exercises at the end of each chapter. The book is also intended to serve as a bridge to important topics that are often left out of a course on ordinary differential equations. In particular, it provides brief introductions to bifurcation theory, center manifolds, normal forms and Hamiltonian systems.
This textbook is addressed to graduate students in mathematics or other disciplines who wish to understand the essential concepts of functional analysis and their applications to partial differential equations. The book is intentionally concise, presenting all the fundamental concepts and results but omitting the more specialized topics. Enough of the theory of Sobolev spaces and semigroups of linear operators is included as needed to develop significant applications to elliptic, parabolic, and hyperbolic PDEs. Throughout the book, care has been taken to explain the connections between theorems in functional analysis and familiar results of finite-dimensional linear algebra. The main concepts and ideas used in the proofs are illustrated with a large number of figures. A rich collection of homework problems is included at the end of most chapters. The book is suitable as a text for a one-semester graduate course.
The core of classical homotopy theory is a body of ideas and theorems that emerged in the 1950s and was later largely codified in the notion of a model category. This core includes the notions of fibration and cofibration; CW complexes; long fiber and cofiber sequences; loop spaces and suspensions; and so on. Brown's representability theorems show that homology and cohomology are also contained in classical homotopy theory. This text develops classical homotopy theory from a modern point of view, meaning that the exposition is informed by the theory of model categories and that homotopy limits and colimits play central roles. The exposition is guided by the principle that it is generally pre...