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Insulin Resistance and Cancer
  • Language: en
  • Pages: 307

Insulin Resistance and Cancer

This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of the cellular and molecular changes characterizing the insulin resistant state, such as hyperinsulinemia, abnormal metabolism and hormone signaling, and how these interact with various tumor characteristics. For example some tumors present increased quantities of the fetal form of the insulin receptor, unique regulation of oxidative (Krebs’ cycle) metabolism (Warburg effect), as well as mutations in various relevant signaling pathways. Finally, the clinical implications of these data are integrated with considerations of insulin “sensitization” and potential metabolic interventions to prevent and treat cancer. It should be noted that while a number of cancers are associated with obesity the authors here have focused primarily on breast cancer as a key and significant model.

The Diabetic Kidney
  • Language: en
  • Pages: 553

The Diabetic Kidney

A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.

Insulin Action
  • Language: en
  • Pages: 189

Insulin Action

In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.

Education of Cancer Healing Vol. IX - The Best Of
  • Language: en
  • Pages: 293

Education of Cancer Healing Vol. IX - The Best Of

  • Type: Book
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  • Published: 2013-06-14
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  • Publisher: Lulu.com

"The Education of Cancer Healing" is the MOST comprehensive and COMPLETE study collection on the history of cancer healing on the market today. Totaling more than 2500 pages filled with invaluable information, this magnum opus holds answers to your questions regarding cancer and many other diseases. These books give you information which is in fact a HEALING DYNAMITE, covered by thousands of scientific and medical studies, independent professionals, and dozens of patient and witness testimonials. With this masterwork, I am giving you the BEST of my own research - the product of $300,000 and the result of more than 20,000 hours of exhaustive and careful research in the field of cancer.My mission is to give you THE SUPER KNOWLEDGE - the foundation for super powers that are within you, so that you can heal yourself of cancer (and any other disease), and live your life to the fullest potential! I will be your guide on your way to POWERFUL HEALTH.

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 1438

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
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  • Published: 2001
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  • Publisher: Unknown

None

Functional Foods for Chronic Diseases, Volume 4: Obesity, Diabetes, Cardiovascular Disorders and AIDS
  • Language: en
  • Pages: 360

Functional Foods for Chronic Diseases, Volume 4: Obesity, Diabetes, Cardiovascular Disorders and AIDS

  • Type: Book
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  • Published: 2009-06-25
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  • Publisher: D&A Inc.

This book reviews functional foods for the prevention and treatment of chronic diseases from multidisciplinary perspective. The report stresses the urgency of modern society to deal with chronic diseases and the need for the creation of functional foods on the basis of natural plant-derived resources. This book represents collections of selected reviews on modern approaches in the prevention and treatment of chronic diseases such as cardiovascular, cancer, diabetes, obesity and AIDS by using the newest achievements in herbal remedies, food additives and non-traditional plants.

Vitamin D
  • Language: en
  • Pages: 2190

Vitamin D

Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This 3e includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must-have resource for anyone working in endocrinology, osteology, bone biology, or cancer research.

County
  • Language: en
  • Pages: 231

County

The amazing tale of “County” is the story of one of America’s oldest and most unusual urban hospitals. From its inception as a “poor house” dispensing free medical care to indigents, Chicago’s Cook County Hospital has been renowned as a teaching hospital and the healthcare provider of last resort for the city’s uninsured. Ansell covers more than thirty years of its history, beginning in the late 1970s when the author began his internship, to the “Final Rounds” when the enormous iconic Victorian hospital building was replaced. Ansell writes of the hundreds of doctors who underwent rigorous training with him. He writes of politics, from contentious union strikes to battles against “patient dumping,” and public health, depicting the AIDS crisis and the Out of Printening of County’s HIV/AIDS clinic, the first in the city. And finally it is a coming-of-age story for a young doctor set against a backdrOut of Print of race, segregation, and poverty. This is a riveting account.

Scientific Directory and Annual Bibliography
  • Language: en
  • Pages: 490

Scientific Directory and Annual Bibliography

  • Type: Book
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  • Published: 1979
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  • Publisher: Unknown

Each issue lists papers published during the preceding year.

Drug Repurposing and Computational Drug Discovery
  • Language: en
  • Pages: 294

Drug Repurposing and Computational Drug Discovery

  • Type: Book
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  • Published: 2023-10-27
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  • Publisher: CRC Press

Drug repurposing is defined as identifying new pharmacological indications from old, existing, failed, investigational, already marketed, or FDA-approved drugs and prodrugs, and applying these new uses in the treatment of diseases other than the drug’s original intended therapeutic use. The application of computational techniques in discovery research not only helps in the development of drugs from leads or existing drug molecules but can also be useful for the repurposing of existing drug candidates. This new volume presents exciting recent advances in drug repurposing and computational approaches for the discovery and development of drugs against certain difficult-to-treat and life-threa...