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Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms. Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.
A significantly expanded third edition, this book provides a comprehensive and concise overview of cardiac arrhythmias and their ECG/telemetry manifestations, including the principles of cardiac electrophysiology, current concepts of pharmacology, clinical features, diagnoses, and state-of-the-art treatments. Additionally, the book emphasizes decision-making strategies in approaching each individual patient and the application of technical innovations in specific clinical situations. Organized into eight parts, beginning chapters introduce the concepts and principles of cardiac electrophysiology, unique rhythms, and ECG waves/signs. These chapters are designed to integrate emerging knowledge...
This book summarises the newest information on seasonal adaptation in animals. Topics include animal hibernation, daily torpor, thermoregulation, heat production, metabolic depression, biochemical adaptations, neurophysiology and energy balance. The contributors to this book present interdisciplinary research at multiple levels ranging from the molecular to the ecophysiological, as well as evolutionary approaches. The chapters of this book provide original data not published elsewhere, which makes it the most up-to-date, comprehensive source of information on these fields. The book’s subchapters correspond to presentations given at the 14th International Hibernation Symposium in August 2012 in Austria. This is a very successful series of symposia (held every four years since 1959) that attracts leading researchers in the field. Like the past symposia, this meeting – and consequently the book – is aimed not only at hibernation but at covering the full range of animal adaptations to seasonal environments. For the next four years, this book will serve as the cutting-edge reference work for graduate students and scientists active in this field of physiology and ecology. .
TASER® Conducted Electrical Weapons are rapidly replacing the club for law-enforcement control of violent subjects within many countries around the globe. A TASER CEW is a hand-held device that delivers a 400-volt pulse with a duration tuned to control the skeletal muscles without affecting the heart at a distance of up to 6.5 meters over tiny wires. If necessary, it begins with an arcing voltage of 50,000 V to penetrate thick clothing; the 50,000 V is never delivered to the body itself. Due to the widespread usage of these devices and the widespread misconceptions surrounding their operation, this book will have significant utility. This volume is written for cardiologists, emergency physicians, pathologists, law enforcement management, corrections personnel, and attorneys.
This compendium gives a comprehensive overview of the advances in fibrillation-defibrillation knowledge ? recognition of fibrillation as a unique life threatening cardiac arrhythmia; discovery of the electric discharge in its double role of culprit and savior; and technological improved contributions.The book stands on the well-known philosophy of Education-Based on Problems (or EBP), that is, take fibrillation as a medical daily problem and search for that knowledge, technique or principle trying to solve it.The book is interdisciplinary, multidisciplinary and transdisciplinary. It addresses undergraduate and graduate biomedical engineering students, physicians going into cardiology, clinical engineers and clinical engineering technicians, nurses, paramedics and emergency medical personnel.
Provides an in-depth study of the theoretical and engineering principles behind the methods and technologies used to solve problems in experimental and clinical cardiac electrophysiology. Each chapter gives an extensive description of the principles underlying a simple method or technology and illustrates how it can be applied to solve problems in
Topic Editor Godfrey Smith is the founder, director and honorary Chief Scientific Officer of Clyde Biosciences Ltd (UK). The other Topic Editors declare no competing interests with regard to the Research Topic subject.
The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascin...