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Antiprotozoal Drug Development and Delivery
This book reviews new promising drug targets for Neglected Tropical Diseases (NTDs), with a special focus on antiprotozoal drugs against trpyanosomatids Trypanosoma cruzi and Leishmania spp. The book offers a comprehensive overview of the most recent studied targets, and it outlines classical and new treatments and delivery strategies. Expert contributors describe new methods of analysis and bio-prospecting for new compounds, and provide a critical perspective of the translational process used in the research and development of new drug candidates. The book will appeal not only to researchers, students and professionals interested in drug development to protozoan diseases, but also to medicinal chemists in general.
Lagoa Santa Karst: Brazil's Iconic Karst Region
This book discusses the Lagoa Santa Karst, which has been internationally known since the pioneering studies of the Danish naturalist Peter Lund in the early 1800s. It covers the speleogenesis, geology, vegetation, fauna, hydrogeology, geomorphology, and anthropogenic use of the Lagoa Santa Karst and is the first English-language book on this major karst area. The area, which has been at the heart of the debate on the origin and age of human colonization in the Americas, is characterized by a classical and scenic karst landscape with limestone cliffs, karst lakes and karst plains, in addition to numerous solution dolines. More than 1,000 caves have been documented in the area, many with significant archeological and paleontological value. Despite its great importance, the Lagoa Santa Karst faces severe environmental threats due to limestone mining and the expansion of the metropolis of Belo Horizonte and its surrounding towns. The growing recognition of the area’s remarkable significance has led to increasing concern, and a number of protected areas have now been established, improving the conservation status of this landmark karst area.
Pharmaceuticals for Targeting Coronaviruses
This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19. Specifically, the book presents 5 chapters written by expert scholar on the following topics: Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19) Potential Antiviral Medicinal Plants against Novel SARS-CoV-2 Infections Caused by SARS Coronaviruses: Main Characteristics, Targets And Inhibitors Natural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19 Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.
Frontiers in Clinical Drug Research – Dementia: Volume 2
Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, sec...
26th International Conference on Plastic Optical Fibres
26thth International Conference on Plastic Optical Fibres, POF 2017 September 13 to 15, 2017 Aveiro, Portugal
Preaching to Latinos
There is a wide and growing gap in the Catholic Church in the United States between the clergy, who are mostly of European descent, and the large percentages of Catholics who identify as Latinos. While the US Church has made a concerted effort to build Hispanic ministries, many clergy and lay ministers are still ill-equipped to understand the cultural background of their parishioners, especially the large numbers who are foreign born. Because of this disconnect, the Church risks missing "the Hispanic Moment" in the US Church, in which the faith and traditions of these newest waves of US immigration could not just exist in parallel to English-language congregations, but enrich and enliven the...
Rethinking Heritage in Precarious Times
Rethinking Heritage in Precarious Times sets a fresh agenda for Heritage Studies by reflecting upon the unprecedented nature of the contemporary moment. In doing so, the volume also calls into question established ideas, ways of working, and understandings of the future. Presenting contributions by leading figures in the field of Heritage Studies, Indigenous scholars, and scholars from across the global north and global south, the volume engages with the most pressing issues of today: coloniality, the climate emergency, the Covid-19 pandemic, structural racism, growing social and economic inequality, and the ongoing struggle for dignity and restitution.Considering the impact of climate chang...
Proceedings of the 3rd International Conference on Smart and Innovative Agriculture (ICoSIA 2022)
This is an open access book. Held as part of the Universitas Gadjah Mada Annual Scientific Conferences (UASC 2022) series, the 3rd International Conference on Smart and Innovative Agriculture (ICoSIA 2022) provides an ideal academic platform for researchers to present the latest research findings and describe emerging technologies and directions in agriculture. This year, the conference will take the theme “Digital transformation, technology, and its solution for agriculture” with seven symposia: Agricultural Big Data Analysis symposium; Agricultural Geography symposium; Land and Environmental Management symposium; Precision Nutrition Technology symposium; Smart and Precision Farming symposium; Smart Genetics Resource Management and Utilization symposium; and Sustainable Food Production symposium.
Augmented Cognition
This book constitutes the refereed proceedings of the 15th International Conference on Augmented Cognition, AC 2021, held as part of the 23rd International Conference, HCI International 2021, held as a virtual event, in July 2021. The total of 1276 papers and 241 posters included in the 39 HCII 2021 proceedings volumes was carefully reviewed and selected from 5222 submissions. AC 2021 includes a total of 32 papers; they were organized in topical sections named: BCI and brain activity measurement physiological measuring and human performance; modelling human cognition; and augmented cognition in complex environments.
