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The book consists of 31 chapters, divided into six parts. Each chapter is written by one or several experts in the corresponding area. The scope of the book varies from the DNA damage response and DNA repair mechanisms to evolutionary aspects of DNA repair, providing a snapshot of current understanding of the DNA repair processes. A collection of articles presented by active and laboratory-based investigators provides a clear understanding of the recent advances in the field of DNA repair.
These powerful, nutrient-rich super-foods will help you lose weight, manage stress and anxiety, build your immune system, look younger, lower blood pressure, fight cancer, and so much more--without side effects. This book also provides preparation and storage tips, healthy and delicious recipes, and little known health-tips and facts for each of these 21 super foods.
Live Better, LONGER In 100 Answers to 100 Questions about How to Live Longer, leading natural health expert Dr. Janet Maccaro reveals the simple things you can do to extend AND improve your life without drugs and medications. You’ll find answers to your most important health questions, including… •Which antioxidants will help me live longer? •Are there natural remedies for my sleepless nights? •How do I cope with issues beyond my control?At the end of our days, we all want to have lived a happy, healthy life and made a difference. 100 Answers to 100 Questions about How to Live Longer will show you how.
DNA is the most important biomolecule ever discovered. Indeed, this molecule bears genetic information from one generation to another. In this regard, DNA bases have a key role in transferring genetic information and data safely. However, there are cellular, genetic, and environmental factors that may damage the different parts of DNA molecules. These damages may result in mutations and cell death. As such, several DNA repair mechanisms have evolved. Over three sections, this book examines many of these mechanisms.
This book is intended for students and scientists working in the field of DNA repair. Select topics are presented here to illustrate novel concepts in DNA repair, the cross-talks between DNA repair and other fundamental cellular processes, and clinical translational efforts based on paradigms established in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.
Diet-Brain Connections fills a void between the fields of nutrition, behavior and cellular and molecular neurosciences by providing an integrated collection of articles that critically dissect the link between what we eat and how the brain develops and functions in health and disease. Key topics covered in depth include: -caloric restriction benefit the brain and retard aging; -effects of dietary antioxidants on brain function and aging; -developmental and function consequences of different dietary fatty acids; -biochemical links between dietary folic acid and psychiatric and neurodegenerative disorders; -effects of nutritional deficit during early development and behavior disorders later in life; -neurochemical basis of the benefits of widely used dietary supplements including creatine and Gingko biloba; -contribution of dietary toxins such as metals and pesticides to neurological disorders.
This volume provides the most recent insight into how abnormalities in the regulation of cell death lead to a variety of diseases. Each chapter in this book is written by an internationally recognized expert on the role of aberrant cell death in the pathogenesis of a particular disease. In addition to various types of cancer and neurodegenerative disorders, this book covers diseases ranging from arthritis to cardiovascular disease to diabetes. The chapters each integrate information obtained from patients with data obtained in experimental models of the disease to arrive at an emerging view of the pathogenic mechanisms of the disease. Applications of this fundamental knowledge to prevention and treatment of the diseases are considered. When taken together with http://www.elsevier.nl/locate/isbn/0444504931Programmed Cell Death, Volume 1, this title will provide graduate students, postdocs and senior investigators in an array of biomedical disciplines invaluable resource for their pursuit of the causes and cures of many different human diseases.
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. The aim of this book is to provide new studies in the field of neuronal apoptosis research.
This book is perfect for leaders across the enterprise who have a difficult time attracting, retaining, understanding ,and communicating with their millennial employees and job candidates. Diving deep into millennial psychology and language using a potent blend of data and anecdotes, stories and history, What Millennials Really Want from Work and Life debunks the many myths around millennials pushed by sensationalist media, showing how millennials want many of the same things as other generations, just more quickly and in a different order and form. Giving helpful context based on his own powerful and unlikely story of continuous struggle and overcoming massive challenges as a millennial, th...
Five young New Yorkers brought together on the verge of greatness - by the chance of fate - do battle to transcend through pangs of City grit and pleasure, to achieve. Helen, a modern woman caught between professions, men and fears, has a stark choice to make. Jacob, a violin prodigy, frantically writes a symphony to win his love and prove himself. Conrad, ambitious Texan in New York, catches a break beyond his wildest dreams, with just one caveat. A childhood sin he can't expunge takes playboy-at-his-peak Lisandro from dream life to damning nightmare, half a world away. Senator's son and journalist Aidan risks everything for story that will make him great. In the dark heart of Africa, against the Russian winter and the heel of influence, in the East-West bazaar of choice and genius mind of Jacob Frenkel, the mettle generation will be forged.