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This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.
This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.
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The seventy-second meeting of the WHO Expert Committee on Biological Standardization was held from 19 to 23 October 2020 by WebEx video conferencing due to the restrictions imposed during the coronavirus disease 2019 (COVID-19) pandemic. The meeting was opened on behalf of the Director-General of WHO by Dr Mariângela Batista Galvão Simão, Assistant Director-General, Access to Medicines and Health Products. Dr Simão welcomed Committee members, meeting participants and observers. Dr Simão began by noting that the Committee had met as recently as August 2020, primarily to address standardization activities related to COVID-19, and that much remains to be learnt about the pandemic. The WHO Solidarity Trial was continuing to facilitate the rapid and robust comparison of potential treatments. Recently published interim results indicated that the four small molecule treatments remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon had little or no benefit in terms of overall mortality or speed of recovery of hospitalized patients – to date only dexamethasone had proved to be effective against severe COVID-19.
This is the book which, when first published in 1965, caused such an uproar in the US State Department that a sharp note of protest was sent to Kwame Nkrumah and the $25million of American "aid" to Ghana was promptly cancelled.
Few books on Ordinary Differential Equations (ODEs) have the elegant geometric insight of this one, which puts emphasis on the qualitative and geometric properties of ODEs and their solutions, rather than on routine presentation of algorithms. From the reviews: "Professor Arnold has expanded his classic book to include new material on exponential growth, predator-prey, the pendulum, impulse response, symmetry groups and group actions, perturbation and bifurcation." --SIAM REVIEW
For almost ten years chaos and fractals have been enveloping many areas of mathematics and the natural sciences in their power, creativity and expanse. Reaching far beyond the traditional bounds of mathematics and science to the realms of popular culture, they have captured the attention and enthusiasm of a worldwide audience. The fourteen chapters of the book cover the central ideas and concepts, as well as many related topics including, the Mandelbrot Set, Julia Sets, Cellular Automata, L-Systems, Percolation and Strange Attractors, and each closes with the computer code for a central experiment. In the two appendices, Yuval Fisher discusses the details and ideas of fractal image compression, while Carl J.G. Evertsz and Benoit Mandelbrot introduce the foundations and implications of multifractals.