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In Ponds, Jane Clark Scharl explores the mysterious relationship between change and repetition: seemingly contradictory, these two weave together so tightly in human existence that they cannot be separated. Speaking in a variety of voices—from a young mother mourning her own mother to Penelope, wife of Ulysses, Persephone, and Theoderic the Ostrogoth—Ponds is a polyphonous meditation on loss and gain, activity and stillness, and the nature of God, both hidden and revealed.
Let’s Call It Home is a slow search for wholeness in the fragmented landscape of language, place, family, and faith. These poems offer themselves as touchstones on the dizzying pilgrimage of ascent and descent towards rooted ground, that place we both hail from and are forever approaching, the home we both know intimately and perennially hunger for. And here, on this road, if the conclusions are provisional and the destination—as seen from this end of things—shifting, the hope compelling us out the door is as certain as the ache that sings us homeward and the unshakable sense of a steadying hand at our backs.
This book provides basic knowledge of the biology, chemistry, and function of oxysterols and its derivatives as well as of phytosterols in numerous human diseases. The book is divided into six sections and begins with an introduction to the biological and chemical properties of oxysterols and its derivatives as well as phytosterols, their synthesis, and the methods currently used for their detection in various biospecimens. The following section discusses in detail the various effects of oxysterols on numerous human diseases, including infectious diseases, inflammatory and autoimmune diseases, atherosclerosis, and cancer, as well as neurological and neuropsychiatric disorders. Importantly, t...
Distant metastases are the main cause of cancer-related death. The onset of the metastatic process can now be assessed in cancer patients by the use of immunocytochemical and molecular methods that allow the identification of disseminated carcinoma cells in regional lymph nodes, peripheral blood or distant organs. There is increasing evidence that the detection and characterization of tumor cells present in bone marrow or peripheral blood can provide clinically important information. In this book, leading experts in the area of micrometastasis research provide an overview that summarizes the current state of research on micrometastatic disease in patients with solid tumors. In each chapter, the technical aspect as well as clinical relevance of micrometastasis detection is discussed. The book addresses basic researchers as well as clinicians involved in the treatment of cancer patients.
In City Nave, Betsy K. Brown explores the architecture of buildings, poems, and souls. Shape makes meaning—in the ornate corridors of cathedrals, the stark expanse of airports, the tidy monastic cells of sonnets, the spiraling stairs of terza rima, and the cluttered corners of memory. City Nave walks the reader through these places in an ongoing search for stories, stability, and sustenance.
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This volume emphasizes the applications and implications of the Geospatial Web and the role of contextual knowledge in shaping the emerging network society. There is a clear focus on applied geospatial aspects. The book has contributions from a very active research community. Containing chapters from renowned researchers and practitioners, this volume will be invaluable to all interested in this field.
Despite having powerful software, microchips, and solid-state detectors that enable analytical chemists to achieve fast, stable, and accurate signals from their instruments, sample preparation is the most important step in chemical analysis. Issues can arise at this step for various reasons, including a low concentration of analytes, incompatibility of the sample with the analytical instrument, and matrix interferences. This volume discusses the basics of sample preparation and examines modern techniques that can be used by both novice and expert analytical chemists. Chapters review microextraction, surface spectroscopy analysis, and techniques for particle, tissue, and cellular separation.