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Modern Mummies
For many, a mummy is an Egyptian pharaoh, wrapped in cloth, found thousands of years later in a pyramid by archaeologists. But mummies need not be ancient. Modern-day mummies can be found under glass in special tombs built in their honor, in private collections where they have come to rest after decades on the carnival circuit, in dissecting rooms of medical schools, and in the basements of funeral homes waiting for decades to be claimed by the next of kin. Stories about the famous (Vladimir Ilyich Lenin, Ho Chi Minh, Eva Peron) and the not-so-famous (Leslie Hansell wanted her body mummified to bask in the sun rather than being buried in the cold ground) mummies are told here in great detail, along with a broader look at the history and process of mummification. The book includes a comprehensive study of the successful prolonged preservation of the human body, and delves into the law and science of modern mummification.
Medicinal Chemistry of Anticancer Drugs
Medicinal Chemistry of Anticancer Drugs, Third Edition provides an updated resource for students and researchers from the point-of-view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. The new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemothe...
Green Chemistry: Synthesis of Bioactive Heterocycles
The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.
Medicinal Chemistry of Anticancer Drugs
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While th...
Drug Discovery and Design Using Natural Products
Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural ...
Sustainable Catalysis
Focussing on catalysis without metals or other endangered elements, this book is an important reference for researchers working in catalysis and green chemistry.
Medicinal Chemistry of Anticancer Drugs
Antitumor chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumor drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, aiming at the rationalization of the action of this type of drug, which would allow the design of new active structures.* Explains the biological basis of cancer treatment and the role of chemists in improving anticancer drugs* Provides the historical background and serves as a comprehensive and practical guide on cancer research and anticancer drug development* Includes coverage of different approaches to treating cancer, drug resistance, and a chapter on cancer prevention
Green Organic Reactions
This book presents important developments and applications of green chemistry, especially in the field of organic chemistry. The chapters give a brief account of green organic reactions in water, green organic reactions using microwave and in solvent-free conditions. In depth discussions on the green aspects of ionic liquids, flow reactions, and recoverable catalysts are provided in this book. An exclusive chapter devoted to green Lewis acid is also included. The potential of supercritical fluids as green solvents in various areas of organic reactions is explained as well. This book will be a valuable reference for beginners as well as advanced researchers interested in green organic chemistry.
To Play the Game
13th October 1972: A Uruguayan Air Force plane, commissioned for a civilian flight, crashes in the Andes. Among the forty passengers are a first-division rugby team, accompanied by family and friends. Hindered by treacherous conditions, the search and rescue efforts cannot locate the wreckage, and are abandoned after eight days. Ten weeks later, two unkempt boys are spotted by a muleteer high in the Chilean foothills. One throws a note to him, across a mountain torrent: I come from a plane that fell in the mountains... In the plane there are still fourteen injured people... Drawing on extensive original research, the author sheds new light on this extraordinary story from a perspective of fi...
