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Bayesian Adaptive Methods for Clinical Trials
Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti
Lost in the Cold War - the Story of Jack Downey, America′s Longest-Held POW
In 1952, John T. "Jack" Downey, a twenty-three-year-old CIA officer from Connecticut, was shot down over Manchuria during the Korean War. The pilots died in the crash, but Downey and his partner Richard "Dick" Fecteau were captured by the Chinese. For the next twenty years, they were tortured, put through show trials, held in solitary confinement, placed in reeducation camps, and toured around China as political pawns. Other prisoners of war came and went, but Downey and Fecteau's release hinged on the United States acknowledging their status as CIA assets. Not until Nixon's visit to China did Sino-American relations thaw enough to secure Fecteau's release in 1971 and Downey's in 1973. Lost ...
Lung Adenocarcinoma: From Genomics to Immunotherapy
Lung cancer is the second most common type of cancer and is the leading cause of cancer death globally. In 2018, almost 2.1 million new cases were diagnosed, accounting for ~12% of the cancer burden worldwide. The malignant stage of lung tumor is known as lung adenocarcinoma, which is most common and is diagnosed in both smokers and non-smokers.There are two main types of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Genomic studies have indicated that more than 80% of lung malignancies are classified as NSCLC, of which adenocarcinoma is a predominant subtype. Although significant progress has been made in treating tumor with targetable driver mutations, ...
Non-melanoma Skin Cancer
This book provides a comprehensive introduction to the current state-of-the-art in skin cancer, exploring the recent developments, appraising the current evidence and providing future directions with particular emphasis on interdisciplinary collaboration and need for clinical trials. It covers all aspects of skin cancers, including epidemiology, pathology, surgical and non-surgical treatments. It will be a valuable reference for oncologists, dermatologists, dermatopathologists, surgeons, allied health care professionals and other specialists and trainees with a special interest in skin cancer who want to update their knowledge in the multidisciplinary management of such patients. The book will be of interest to medical physicists and radiographers who would like an overview of the current practice in skin cancer. The book can be used by students in medicine, nursing, radiography and medical physics. Features Provides a comprehensive review of all aspects of skin cancer management. Edited by experts in the area, with interdisciplinary and international collaborators. Promotes a 'Bigger picture' approach to the topic with multidisciplinary insight.
Body Self & Soul
A wide range of ancient Eastern and modern Western philosophies are connected in this exciting new therapy. Free your bodily tensions and release long-held emotions, enhancing your mental and physical health. Rosenberg's Integrative Body Psychotherapy helps develop both personal and internal growth, focusing on the whole person — the body, mind, emotions and spirit. An integration of various disciplines, this approach is ideal for professionals looking to develop a holistic and integrated philosophy of health. This book helps both professionals and lay readers learn: -The basic tools of Integrative Body Psychotherapy -Segments of the body, and how they work together -The stages in development of the self -The physical/energetic level of sexuality -The intra-psychic level of sexuality -The interpersonal level of sexuality -The transpersonal experience What readers are saying about this book: The authors' broad perspective is a welcome relief from the narrowness of most self-development systems. Body, Self, and Soul is thoughtful, practical, and very well informed. — Michael Murphy, founder of Esalen Institute
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