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Lung cancer is the second most common type of cancer and is the leading cause of cancer death globally. In 2018, almost 2.1 million new cases were diagnosed, accounting for ~12% of the cancer burden worldwide. The malignant stage of lung tumor is known as lung adenocarcinoma, which is most common and is diagnosed in both smokers and non-smokers.There are two main types of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Genomic studies have indicated that more than 80% of lung malignancies are classified as NSCLC, of which adenocarcinoma is a predominant subtype. Although significant progress has been made in treating tumor with targetable driver mutations, ...
This book offers outstanding approaches to understanding the role of the tumor microenvironment (TME) in cancer development and metastasis. The TME, with its multifaced role, is fundamental in the control and exacerbation of almost all cancer types. The outcome of many solid tumors is dependent on the modulation of the TME. Local tumor immunity, which is crucial in the control of cancer promotion, is one of the leading compounds of the TME. This book presents new insights and provides detailed and updated descriptions of the role of the TME in the control and the development of almost all cancer types. This book is an authentic source of knowledge, useful for researchers, medical doctors, students, and all individuals interested in understanding the mechanisms of cancer control and development.
This book provides a complete overview on the latest available technologies in dermatology, while discussing future trends of this ever-growing field. This handy guide provides clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today. It also includes a section on imaging techniques for the evaluation of skin tumors, with chapters devoted to dermoscopy, in vivo and ex vivo reflectance confocal microscopy, high frequency ultrasound, optical coherence tomography, and a closing part on latest approaches to wound management. Completed by over 200 clinical images, Current Technology in Practical Dermatology: Non-Invasive Imaging, Lasers and Ulcer Management is both a valuable tool for the inpatient dermatologist and for physicians, residents, and medical students in the field.
Si afferma che le imprese devono cambiare continuamente, operare su scala internazionale, reinventare i prodotti e servizi e mirare ad un miglioramento continuo dei processi. È necessario potenziare lo sviluppo del sapere nell’organizzazione, sia dal punto di vista gestionale che secondo aspetti relazionali e legati alla sfera della leadership. Indubbiamente lo scenario economico-sociale attuale richiede grande capacità di adattamento a cambiamenti continui e immediati. I modelli tradizionali d’impresa non reggono più questa pressione e devono perciò essere superati; sono limitati da una scarsa attenzione rivolta al cliente e da un eccessivo accentramento dell’azienda rispetto al p...
Molecular and Cellular Therapeutics aims to bring together key developments in the areas of molecular diagnostics, therapeutics and drug discovery. The book covers topics including diagnostics, therapeutics, model systems, clinical trials and drug discovery. The developing approaches to molecular and cellular therapies, diagnostics and drug discovery are presented in the context of the pathologies they are devised to treat.
Have you ever imagined taking a trip down memory lane and making sense of all your relationships?The courage of an idea, the power of a pen and a list of 500 positive words will tell you the over-the-top story of a romantic Italian woman who found the meaning of life, in the name of Love. "Do you speak Amore?" is an autobiography celebrating her 40 years with an invitation to self care, in silence. If you have been dreaming of just dropping everything and taking off but yet haven't managed, allow yourself to be transported between Tuscany, America, Japan, Brazil, Portugal and Africa in the pages of this book.
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