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Bayesian Adaptive Methods for Clinical Trials
Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti
Anthology of Statistics in Sports
The unlikely worlds of sports fans and statisticians collide in this interesting and accessible collection of previously published articles on the use of statistics to analyze sports, which the editors have thoughtfully culled from a variety of American Statistical Association (ASA) publications. Heavily weighted in the areas of competition (rating players and teams, evaluating strategies for victory), the articles vary in mathematical complexity, but most will be accessible to readers with a general knowledge of statistics. Newly written material from the editors and other notable contributors introduces each section of the book, and a chapter with suggestions on using the articles in the c...
Nutrition for the Hospitalized Patient
This work offers detailed coverage of the biochemical and metabolic framework that forms the basis for the current theory of nutrition support. It presents analyses of the practical aspects of providing nutrition to hospitalized patients, and examines nutrition support in critical care and sepsis, cancer, gastrointestinal disease, cardiac and pulmonary disease, burns, renal failure, newborns and children, pregnancy, AIDS, neurological impairment and perioperative patients.
Medical Biostatistics
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Third Edition focuses on the statistical aspects of medicine with a medical perspective, showing the utility of biostatistics as a tool to manage many medical uncertainties. The author concludes "Just as results of medical tests, statistical results can be false negative or
The Vagus-Immune Connection
This comprehensive guide delves into the intricate relationship between the vagus nerve and immune regulation, providing invaluable insights and practical strategies for understanding chronic illnesses like migraine, anxiety, BPD, cognitive dysfunction, stroke, hypertension, IBS, and more. Engineer, inventor, and vagus nerve expert J. P. Errico distills the latest scientific research and technological advancements to offer an easy-to-understand guide to bolstering your immune system and enhancing resilience against pathogens and diseases. With The Vagus-Immune Connection, you will: Gain a deep understanding of how the vagus nerve influences the immune system, from its role in controlling inflammation to its impact on autoimmune conditions; Discover practical techniques to effectively manage stress, a major contributor to immune dysregulation; Enhance immune resilience and disease prevention; Optimise cellular energy metabolism to improve neurodevelopment and cognitive function. Whethe
Theory of Drug Development
Theory of Drug Development presents a formal quantitative framework for understanding drug development that goes beyond simply describing the properties of the statistics in individual studies. It examines the drug development process from the perspectives of drug companies and regulatory agencies. By quantifying various ideas underlying drug development, the book shows how to systematically address problems, such as: Sizing a phase 2 trial and choosing the range of p-values that will trigger a follow-up phase 3 trial Deciding whether a drug should receive marketing approval based on its phase 2/3 development program and recent experience with other drugs in the same clinical area Determinin...
Bayesian Methods in Epidemiology
Written by a biostatistics expert with over 20 years of experience in the field, Bayesian Methods in Epidemiology presents statistical methods used in epidemiology from a Bayesian viewpoint. It employs the software package WinBUGS to carry out the analyses and offers the code in the text and for download online.The book examines study designs that
Patient-Reported Outcomes
Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the healt
Controversial Statistical Issues in Clinical Trials
In clinical trial practice, controversial statistical issues inevitably occur regardless of the compliance with good statistical practice and good clinical practice. But by identifying the causes of the issues and correcting them, the study objectives of clinical trials can be better achieved. Controversial Statistical Issues in Clinical Trials covers commonly encountered controversial statistical issues in clinical trials and, whenever possible, makes recommendations to resolve these problems. The book focuses on issues occurring at various stages of clinical research and development, including early-phase clinical development (such as bioavailability/bioequivalence), bench-to-bedside trans...
From Goddess to Mortal
Autobiography of the author who was worshipped as virgin goddess from 1984-1991, in Nepal.
