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Immunology and Infectious Disease
This unique volume provides a mechanistic look at key aspects of the inflammatory response seen in critical illness. Key cells and mediators involved in the innate inflammatory response and the pathways employed to combat infection or respond to injury are emphasized. It has become clear that a delicate balance exists to allow eradication of infection with minimal immune-mediated tissue injury in the process. For this reason an up-to-date discussion of how the inflammatory response down regulates itself has been included. The inflammatory response in the critically ill is vastly different than in healthy hosts. For this reason, discussions about the mechanisms of pharmacologic immune suppres...
From Bench to Market
This text charts the process of industrial chemical synthesis, from the first discovery of a molecule, or new chemical entity, to its entry in the marketplace as a drug, with all the development needs and problems that take place along the way.
Stress and Cardiovascular Disease
The main aim of this book is to evaluate the concept of stress and provide tools for physicians to identify patients who might benefit from stress management. This will incorporate a detailed description of the physiological and pathophysiological consequences of acute and chronic stress that might lead to cardiovascular disease. The book will aim to critically evaluate interventional research (behavioural and other therapies) and provide evidence based recommendations on how to manage stress in the cardiovascular patient. Our intentions are to define and highlight stress as an etiological factor for cardiovascular disease, and to describe an evidence based "tool box" that physicians may use to identify and manage patients in whom stress may be an important contributing factor for their disease and their risk of suffering cardiovascular complications.
Clinical Nephrotoxins
GEORGE A. PORTER information is an international commodity whose The field of clinical nephrotoxicity involves toxins of interpretation and application are strongly influenced diverse origin and exposure. A significant contribution by both the cultural and ethnic background of the to this problem arises from registered and non-regis observer. The opportunity to share in the rich diversity tered drugs either prescribed or purchased over the of the international scientific community was a fun counter. Another major contributor comes from occu pational or industrial exposures. Each situation pre damental goal of this endeavor. To participate as sents the nephrologist with unique challenges con ...
Jewish Migration to South Africa
The Poor Jews' Temporary Shelter in London, England provided shelter for Jews emigrating from all over Europe, although most of those listed were from Lithuania. Includes name, date of arrival, age, birthplace, ship and date of departure. Lists occupants who ultimately settled in South Africa.
Annual Reports on Fermentation Processes
Annual Reports on Fermentation Processes, Volume 2 focuses on fermentation research and developments. This book discusses the production of fermentable sugars from cellulosic materials, fermentation products from cellulosic materials, and models and methods for computer control of fermenters. The kinetic hysteresis in enzyme and fermentation systems, immobilization methods, and process control on cultivation of microorganisms are also elaborated. This text likewise covers the yeast-derived products, nuclear modified cephalosporins, and biosynthetic pathways and metabolic regulation. Other topics include the microbial transformations of antibiotics and cytotoxic and antitumor compounds from fermentations. This volume is a good source for students and specialists conducting work on the significant developments concerning fermentation processes.
Numerical Methods and Optimization
Initial training in pure and applied sciences tends to present problem-solving as the process of elaborating explicit closed-form solutions from basic principles, and then using these solutions in numerical applications. This approach is only applicable to very limited classes of problems that are simple enough for such closed-form solutions to exist. Unfortunately, most real-life problems are too complex to be amenable to this type of treatment. Numerical Methods – a Consumer Guide presents methods for dealing with them. Shifting the paradigm from formal calculus to numerical computation, the text makes it possible for the reader to · discover how to escape the dictatorship of those part...
