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Cell Membrane
This publication presents the structure and function of biological membranes to improve the understanding of cells in both normal and pathogenic states. Recently, vast amounts of new information have been accumulated, especially about pathological conditions, and there is now much evidence correlating genotypes and phenotypes in normal and disease states. This book surveys the most recent findings in research on the molecular biology, biochemistry, and genetics of the membranes of human red blood cells.
Neuropoisons
Poisons are topics of multidisciplinary concern. The clinician and the pathologist are sensitive to instances of human poisoning. The laboratory researcher, whether pharmacologist, physiologist, or biochemist, is oriented toward molecular modes of poison action. Both clinician and researcher are eager to learn of poisons that can be used as therapeutic agents or methodological tools. This volume is an attempt to underscore the multidisciplinary charac ter of neuropoisons. Six poisons of animal origin which are receiving considerable clinical and research attention are discussed. Each poison is presented first as a clinical entity, then as a topic of investigative research, and finally as an agent useful to the study of nerve function. Because no single volume on neuropoisons can be exhaustive, an attempt at balance is offered as compensation. Two snake venoms, two marine poisons, and two bacterial toxins are presented in detail. In the sequel to this volume, attention will be focused on representative neuro poisons of plant origin.
High Performance Non-Oxide Ceramics II
The nitrides and carbides of boron and silicon are proving to be an excellent choice when selecting materials for the design of devices that are to be employed under particularly demanding environmental and thermal con- tions. The high degree of cross-linking, due to the preferred coordination numbers of the predominantly covalently bonded constituents equalling or exceeding three, lends these non-oxidic ceramics a high kinetic stability, and is regarded as the microscopic origin of their impressive thermal and mechanical durability. Thus it does not come as a surprise that the chemistry, the physical properties and the engineering of the corresponding binary, ternary, and even quaternary co...
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease
Completely updated for its Fourth Edition, this book is the most comprehensive, current review of the molecular and genetic basis of neurologic and psychiatric diseases. More than 120 leading experts provide a fresh, new assessment of recent molecular, genetic, and genomic advances, offer new insights into disease pathogenesis, describe the newest available therapies, and explore promising areas of therapeutic development. This edition features an updated section on psychiatric disease and expanded, updated chapters on human genomics, gene therapy, and ethical issues. Six new chapters cover congenital myasthenic syndromes, hereditary spastic paraplegia, ion channel disorders, the phakomatoses, beta-galactosidase deficiency, and prion diseases. A Neurologic Gene Map describes the chromosome locus of all the genetic diseases and their gene product where known. The fully searchable online text will be available on a companion Website. (www.rosenbergneuroandpsychdisease.com)
Endocrinology of Aging
Distinguished physicians critically review the clinical consequences of the endocrinological changes that occur with aging-in both men and women-and examine the use of hormonal therapy to reduce them. Topics range from bone disease and water balance in all older people, to androgen deficiency in aging males, gynecomastia, and menopause. The authors also discuss Type II diabetes in persons over 65, emphasizing the cognitive benefits of good glycemia control, and the interaction of nutrition and metabolism, focusing on hypocholesterolemia, obesity, the anorexia of aging, trace elements, and vitamins. The aging of the sympathetic nervous system and its impact on hypertension in the elderly is also covered. Timely and authoritative, Endocrinology of Aging offers endocrinologists, geriatricians, and primary care physicians critical insight into the endocrine problems of our rapidly growing elderly population.
Self-Trapped Excitons
Self-Trapped Excitons discusses the structure and evolution of the self-trapped exciton (STE) in a wide range of materials. It includes a comprehensive review of experiments and extensive tables of data. Emphasis is given throughout to the unity of the basic physics underlying various manifestations of self-trapping, with the theory being developed from a localized, atomistic perspective. The topics treated in detail in relation to STE relaxation include spontaneous symmetry breaking, lattice defect formation, radiation damage, and electronic sputtering.
Oral Cephalosporins
This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci ...
Temporary Anchorage Devices in Clinical Orthodontics
Provides the latest information on all aspects of using temporary anchorage devices in clinical orthodontics, from diagnosis and treatment planning to appliances and applications Written by some of the world’s leading experts in orthodontics, Temporary Anchorage Devices in Clinical Orthodontics is a comprehensive, up-to-date reference that covers all aspects of temporary anchorage device (TAD) use in contemporary orthodontics. Taking a real-world approach to the subject, it covers topics ranging from diagnosis and treatment planning to the many applications and management of complications. Case studies demonstrate the concepts, and high-quality clinical photographs support the text through...
Baran and Dawber's Diseases of the Nails and their Management
The Scientific and Clinical Encyclopedia of the Nail The human nail provides a complex structure that supports fine manipulation of objects while protecting the extremities. Diseases of the nail disrupt this function. They can cause pain and discomfort, cause disfigurement and are often unsightly with a profound effect on the sufferer's self confidence. Baran & Dawber's Diseases of the Nails and their Management has long been recognized as the pre-eminent authority on nail disease. The 13 chapters encompass the scientific and clinical management of all abnormalities of the nails including: Imaging of the Nail Unit The Nail in Dermatologic Disease The Nail in Systemic Disease Congenital and H...
Devices for Cardiac Resynchronization:
Here is an essential text for cardiologists, heart surgeons, intensive care specialists and anyone interested in pacing. It is a comprehensive guide to contemporary devices used in the resynchronization of patients’ heartbeats. The treatment of congestive heart failure by implanted biventricular pacemakers, or cardiac resynchronization, has revolutionized the practice of implanting pacemakers and defibrillators. More cardiac resynchronization therapy devices than conventional pacemakers are now being implanted and the numbers are growing worldwide.
