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This first-of-its-kind reference book presents detailed information on the structure, composition and casualties of the Confederate Army of Northern Virginia during its entire four year history, 1861-1865. Readers will know at a glance who commanded each unit, and when. Unit strengths and casualties are given for the Army's major campaigns. Meticulously compiled from the 128 volumes of the Official Records, this reliable source provides a comprehensive record of the Army's development, from its formation to its demise.
Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.
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How does the foetus - a foreign body - survive inside the mother? The placenta is the extraordinary organ that allows this to happen; but this remarkable feat of evolution is only just being fully appreciated by science. Y.W. Loke explores the fascinating nature of the placenta and what it can tell us about evolution, development, and genetics.
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