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This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their...
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Proceedings of the Seventh International Conference on Basement Tectonics, held in Kingston, Ontario, Canada, August 1987
The Early Proterozoic Michigamme Formation of northern Michigan was deposited in the southeastern part of the Animikie basin. The formation conformably overlies the Goodrich Quartzite and comprises three widespread members a lower member of thin-bedded shale, siltstone, and sandstone; the Bijiki Iron-formation Member; and an upper member of tur- biditic graywacke, siltstone, and mudstone and a few local members. The Goodrich Quartzite is interpreted as having been deposited in a tidally influenced shallow marine environ- ment. The lower member of the Michigamme is interpreted as having been deposited in a tidally influenced environment, the iron-formation member as having been deposited belo...
Proceedings of the NATO Advanced Study Institute, Oslo, Norway, July 27-August 5, 1977