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"Upper Airway Stimulation Therapy for Obstructive Sleep Apnea provides the current state of knowledge regarding this novel therapy. It reviews the pathophysiological basis of sleep apnea and the specific mechanism by which upper airway stimulation provides airway support in this disorder. It also provides practical insights into this therapy related to patient selection, clinical outcomes, surgical technique, long term follow up, adverse events, as well as recommendations for those aspiring to develop an upper airway stimulation program. It provides an overview of unique populations and circumstances which may extend the utility of the procedure, and which may provide challenges in management, as well as thoughts on the future of this technology. This textbook is intended for all practitioners who have interest or care for sleep disordered breathing including Sleep Medicine Physicians, Pulmonologists, Otolaryngologists, Primary Care Practitioners, as well as physician extenders"--
With contributions by numerous experts
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
International Review of Cytology
The aim of this book is to provide health care professionals with an overview of the main aspects of recent advances in sleep medicine, with an emphasis on advancing basic science into clinical medicine. It is divided into three main parts. The first part is to cover the basic sleep mechanisms which includes genetics in sleep, and neural and humoral regulation of sleep and wakefulness. The second part focuses on the epidemiology of sleep, and the final part consists of the pathophysiological mechanisms of snoring and sleep apnea and other common sleep disorders as well as the consequences. The content of this book is written by experts and sleep specialists from all over the world and this book aims to optimize the health of individuals by “translating” bench side findings into clinical practice.
Comprehensive Natural Products Chemistry
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
The most common problems for which patients present to the Emergency Department are neurological disorders, including stroke, syncope, back pain and headache. The etiology of the patient's symptoms may be life-threatening, that is, when headache is due to subarachnoid hemorrhage or meningitis, or life-altering, that is, when back pain or weakness is due to spinal cord compression, if not diagnosed and treated urgently. This is a comprehensive textbook of the disorders that are neurological emergencies, including their differential diagnosis, diagnosis and treatment. Designed for any practitioner who makes time-sensitive decisions, Emergency Neurology is an indispensable, one-stop resource to aid your clinical decision-making.