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Origins of Human Neuropathology: The Significance of Teneurin-Latrophilin Interaction
We are delighted to introduce this new special issue on “The Origins of Neuropathology: The Roles of Teneurins and Latrophilins”. Although the title may seem particularly bold, and indeed, perhaps presumptuous, we the editors, think our title well warranted based on the findings and interpretation provided by a dedicated group of researchers who have developed this field over the last 25 years. In this publication, we introduce the readers to researchers whom have pioneered this field, and those whom have played an essential role in developing this research direction. Now, together, their combined work have elucidated a novel ligandreceptor network that evolved during the earliest period...
Neuroendocrinology
There has been an explosion of interest in the field of neuroendocrinology over the last twenty years with the discovery of neurohormones regulating virtually everything from growth and development to sexual and aggressive behavior. This book provides a much-needed introduction to neuroendocrinology from a zoological and evolutionary perspective. It covers the evolution, development and description of the neuroendocrine system throughout the animal kingdom. Specific topics covered include: The Evolution of early neuroendocrine systems in primitive animals Structural characterisation, molecular biology and biochemistry of neuroendocrine agents A profiles section on unusual aspects of neuroendocrine physiology written by leaders in the field A unique section on the actions of environmental chemicals effect neuroendocrine systems in various species
Current Views of Hypothalamic Contributions to the Control of Motivated Behaviors
The increasing availability of technologies for interrogating genetically targeted neurons is driving a resurgence of empirical research aimed at determining the structure and function of the neural systems that control motivated behaviors. This has refocused attention on the hypothalamus, whose central role in behavioral control was identified about a century ago. As a result, new insights into hypothalamic contributions to the control of motivated behaviors are emerging, driven not only by the application of new technologies, but also by the application in parallel of iteratively refined established techniques, and increasingly by informatics approaches applied to maturing neuroscience databases. With this renewed interest in decrypting hypothalamic contributions to the control of motivated behaviors, it is timely to provide an updated overview that bridges current insights and historical foundations.
Neuroanatomy of Neuroendocrine Systems
In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems. The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques. In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones. Fo...
Peptides: The Wave of the Future
This volume contains the proceedings of the Second International Peptide Symposium and the Seventeenth American Peptide Symposium, held on 9-14 June, 2001, at the Town and Country Resort in San Diego, California. The biennial meeting was held under the auspices of the American Peptide Society. In addition to the main Symposium, we were honored to have the Merrifield Satellite Symposium, honoring Bruce Merrifield's accomplishments on his 80th birthday. Over 1250 participants from around the world attended the lectures, posters, and exhibits. Reflecting the international nature of the Symposium, there were participants from 37 countries in attendance. In addition to the 75 plenary lectures, there were over 575 poster presentations, and 70 commercial exhibits as well as booths from the American, Australian, Chinese, European, and Japanese Peptide Societies. These proceedings include plenary lectures and oral and poster presentations collected from a wide diversity of topics providing a truly comprehensive and up-to-date overview of the field of peptide science. This publication contains essential reference information for researchers active in peptide science.
Melanin-Concentrating Hormone and Sleep
This book offers a compilation of papers on the role of melanin-concentrating hormone (MCH) in sleep, sleep disorders and neuroendocrine functions. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from the anatomical structure and physiology of the MCH system to the connection with other systems influencing sleep and diseases like anxiety and depression. The potential of MCHR-1 antagonists as anxiolytic/antidepressant drugs is also reviewed. The book will represent an interdisciplinary guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, psychologists, and behavioral sleep medicine specialists.
Handbook of Artificial Intelligence in Education
Gathering insightful and stimulating contributions from leading global experts in Artificial Intelligence in Education (AIED), this comprehensive Handbook traces the development of AIED from its early foundations in the 1970s to the present day.
What Is Restless Leg Syndrome (RLS) a.k.a. Willis–Ekbom disease (WED) ? A Concise Overview.
What Is Restless Leg Syndrome (RLS) a.k.a. Willis–Ekbom disease (WED) ? A Concise Overview. Restless legs syndrome (RLS)—also known as Willis-Ekbom Disease, primary RLS, and idiopathic RLS—is a neurological disorder that causes unpleasant or uncomfortable sensations in the legs and an irresistible urge to move them. Symptoms commonly occur in the late afternoon or evening hours and are often most intense at night when one is resting. RLS can severely disrupt the sleep, making it difficult to fall asleep or return to sleep after waking up. RLS is both a sleep disorder, because the symptoms are triggered by resting and attempting to sleep, and a movement disorder, because people with RLS are forced to move their legs in order to relieve symptoms. It occurs in both males and females, although females are more likely to have it. Many individuals who are severely affected are middle-aged or older, and the symptoms typically become more frequent and last longer with age. RLS is generally a lifelong condition for which there is no cure. However, treatments are available to ease symptoms. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
The Acth Axis: Pathogenesis, Diagnosis and Treatment
"In this outstanding volume, Dr. Gaillard has assembled a team of international experts who have written one of the most comprehensive treatises on this topic. Ranging from fundamental molecular developmental mechanisms of the corticotroph cell, to the treatment of Cushing's Disease, these chapters provide a cutting edge overview of the pathogenesis, diagnosis and treatment of disordered hypothalamic-pituitary-adrenal function. Especially noteworthy are the inclusion of chapters on appetite control and neuro-immunomodulation, reflecting the recent exciting advances in these fields. The student of Cushing's Disease and the HPA axis will find elucidation of the latest basic scientific advances, coupled with patient friendly guidelines for clinical diagnosis and management of an extremely challenging neuroendocrine disorder. The repute of the authors, highest quality writing, lucid text and comprehensive coverage of the topics, all blend to result in an excellent text."
