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The Role of the Fungal Cell Wall in Host-Fungal Interactions
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Emerging and Re-emerging Infectious Diseases of Livestock
This book provides comprehensive knowledge on diseases in livestock that are caused by viruses, parasites and bacteria. Emerging and re-emerging pathogens are presented in detail for various animal groups and in-depth insights into pathogenesis and epidemiology will be provided for each of them. In addition, state-of-the-art treatment possibilities, control measures as well as vaccination strategies are discussed. The recent years have witnessed a sharp increase in the number of emerging and re-emerging infectious diseases of livestock and many of these, including Influenza, Corona and Hanta are of public health importance. The reasons for this development are manifold:changes in the climate, life cycle of vectors and increased global travel. Also, due to extensive deforestation, livestock are increasingly coming in direct contact with wild animals that are reservoirs of many emerging pathogens. Recent progress in diagnosis and management of emerging infectious diseases are also topic of this book.
The Interplay of Microbiome and Immune Response in Health and Diseases
[Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structu...
Immunomodulatory Effects of Drugs for Treatment of Immune-Related Diseases
More than 90% of diseases possess immunological abnormalities. Disorders such as inflammation, hypersensitivity, autoimmunity and immunodeficiency are simple examples of how the immune system misinterprets its surroundings and goes awry. Multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel diseases, among many others are manifestations of immune cells attacking normal tissues. On the other hand, damping the immune system leads to diseases such as cancer, AIDS, and severe combined immunodeficiency. The last ten years witnessed an explosion in developing drugs that target the immune system. Several novel monoclonal antibodies have been approved for treatme...
Targeted Antigen Delivery: Bridging Innate and Adaptive Immunity
The most efficient way to mount a sustained immune response is to target antigens to antigen presenting cells that trigger both innate and adaptive immune responses. A comprehensive view of the current approaches to the design of new antigenic formulations will enhance our understanding and perspective of targeted immunotherapy. The aim of this Research Topic is to provide an overview of the currently adopted targeting strategies by a collection of articles on: 1.Novel approaches of antigen targeting for immunotherapeutic strategies against cancer and/or infectious diseases. 2. Diversity and biology of dendritic cell subsets in human and mouse. 3. Combined strategies for the delivery of antigens and adjuvant molecules that stimulate innate immune responses and their influence on the quality of immune responses. 4. Impact of the receptor mediate intracellular trafficking on antigen presentation.
