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Parasite Genomics Protocols, Second Edition expands upon the previous edition with current, detailed methodologies that have been adapted to research parasites in the post genomic era. With new chapters on parasite studies, helminth pathogens, and protocols for undertaking other large-scale ‘omics’ methodologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Parasite Genomics Protocols, Second Edition offers a wide-ranging collection of diverse methods and protocols for further study into these unique organisms.
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in molecular evolution rely heavily on statistical procedures based on stochastic process modelling and advanced computational methods including high-dimensional numerical optimization and Markov Chain Monte Carlo. This book provides an overview of the statistical theory and methods used in studies of molecular evolution. It includes an introductory sect...
Each chapter presents a detailed background of the described method, its theoretical foundations, and its applicability to different biomedical material. Updated chapters describe either the most popular methods or those processes that have evolved the most since the past edition. Additionally, a large portion of the volume is devoted to clinical cytometry. Particular attention is paid to applications of cytometry in oncology, the most rapidly growing area.
This volume provides reviews and details of the quality, safety and efficacy for some of the top-selling botanicals worldwide, including black cohosh, chamomile, comfrey, echinacea, garlic, ginkgo, ginseng, kava, milk thistle, St John's wort and valerian. The work was written based on a systematic review of the scientific literature from 1975-2000.;Each review includes a brief introduction, a section on quality including a definition of the crude drug, geographical distribution, and a listing of the major chemical constituents. The safety and efficacy sections summarize the medical uses, pharmacology, contraindications, warnings, precautions, adverse reactions, dose and dosage forms. The safety and efficacy sections were written for a busy health-care professional, and should enable one to ascertain which clinical uses are supported by clinical data, without having to read through all the pharmacology. Each chapter is fully referenced, enabling the reader to access further information when necessary.
Design techniques for nonlinear microwave circuits are much less developed than for linear microwave circuits. Until now there has been no up-to-date text available in this area. Current titles in this field are considered outdated and tend to focus on analysis, failing to adequately address design and measurement aspects. Giannini and Leuzzi provide the theoretical background to non-linear microwave circuits before going on to discuss the practical design and measurement of non-linear circuits and components. Non-linear Microwave Circuit Design reviews all of the established analysis and characterisation techniques available and provides detailed coverage of key modelling methods. Practical...
The 12th European Radar Conference (EuRAD 2015) is the major European event for the present status and the future trends in the field of radar technology, system design, and applications It is the ideal event to keep up to date with the latest achievements in the field of radar and to interact with international experts from industry and academia The conference brings together researchers and radar developers from all over the world to stimulate development of new products and services International experts will present keynote papers on topics of current importance and on the latest advances Tailored short courses and workshops will complement the programme
The definitive book on reverse shoulder arthroplasty from leading orthopaedic shoulder surgeons This masterful book from top experts provides clinical insights on reverse shoulder arthroplasty gleaned from hands-on refinement of shoulder replacement techniques. Years of significant biomechanical and clinical research yielded invaluable knowledge that led to important improvements in functional outcome and implant durability. Among these refinements were stronger polyethylene derivatives, better ingrowth technology, and improved connection devices. As the durability and longevity of implant technology increased, younger active patients became suitable candidates for this procedure. In fact, R...
The battle for the United Planets hits a fever pitch as the galactic conqueror Mongul beats some of the rulers of the galaxy to death and then heads for Earth! The only thing standing in his way? Superman! Meanwhile, back on Earth, the truth that Clark Kent is Superman continues to spiral out all over the world, and now the Daily Planet’s competition is gunning for his wife, Lois Lane!