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Topic Editor Prof. Xing is in collaboration with ATCC (https://www.atcc.org/) on testing some of their cell lines in research. All other Topic Editors declare no competing interests with regards to the Research Topic subject.
This volume focuses on different aspects of language development. The contributions are concerned with similarities and differences between first and second language acquisition, the acquisition of sentence structure and functional categories, cross-linguistic influence in bilingual first language acquisition as well as the relation between language acquisition, language contact and diachronic change. The recurrent topic of the volume is the link between linguistic variation and the limitation of structural variability in the framework of a well-defined theory of language. In this respect, the volume opens up new perspectives for future research.
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What is the relationship between habits and emotions? What is the role of the embodiment of emotions in a cultural habitat? What is the role of the environment for the formation of emotions and subjectivity? One way to address these questions is through discussing an emotional habitus - a set of habits and behavioral attitudes involving the body that are fundamental to emotional communication. But this set of habits is not independent of context; it takes place within a specific emotional habitat in which other bodies play a crucial role. Together, these constitute the foundation of sociocultural communities, psychologies of emotions and cultural practices - and they have much to contribute to the study of emotions both for cognition and aesthetics. Thus, the challenge of addressing these questions cannot be faced by either the sciences or the humanities alone. At the Berlin-based conference: Emotion and Motion, scholars gathered from various disciplines to broaden perspectives on the interdisciplinary field of embodied habits and embodied emotions. This book offers a new view on the related field of habitus and the embodied mind.
This book sheds new light on component surfaces and the scientific fundamentals of their creation, characterization, and application. The book also provides a new interdisciplinary perspective on the topic, studying component surfaces with a multiscale approach and linking fundamental and applied research. The book builds on the success of the coordinated research project funded by Deutsche Forschungsgemeinschaft (DFG) from 2011 – 2023: the CollaborativeResearch Center CRC 926 “Microscale Morphology of Component Surfaces (MI-COS)”, in which, over the years, 100+ researchers have co-operated at the University of Kaiserslautern, Germany, and affiliated institutes, yielding 500+ scientifi...
With more and more interest in how components of biological systems interact, it is important to understand the various aspects of systems biology. Kinetic Modelling in Systems Biology focuses on one of the main pillars in the future development of systems biology. It explores both the methods and applications of kinetic modeling in this emerging field. The book introduces the basic biological cellular network concepts in the context of cellular functioning, explains the main aspects of the Edinburgh Pathway Editor (EPE) software package, and discusses the process of constructing and verifying kinetic models. It presents the features, user interface, and examples of DBSolve as well as the pr...
There is no doubt that nowadays, biology benefits greatly from mathematics. In particular, cellular biology is, besides population dynamics, a field where tech niques of mathematical modeling are widely used. This is reflected by the large number of journal articles and congress proceedings published every year on the dynamics of complex cellular processes. This applies, among others, to metabolic control analysis, where the number of articles on theoretical fundamentals and experimental applications has increased for about 15 years. Surprisingly, mono graphs and textbooks dealing with the modeling of metabolic systems are still exceptionally rare. We think that now time is ripe to fill this...
A fundamental reassessment of the ways that racial policy worked and was understood under the Third Reich. Leading scholars explore race's function, content, and power in relation to society and nation, and above all, in relation to the extraordinary violence unleashed by the Nazis.
Cells are permanently challenged by DNA damage which can be induced by environmental factors such as UV irradiation or intracellular factors like reactive oxygen species. As damaged DNA can lead to malignant transformations, a complex signaling network termed DNA damage response is activated upon detection of DNA lesions and allows to maintain genomic integrity. The two transcription factors NF-κB and p53 regulate cell fate decisions upon genotoxic stress and therefore play crucial roles in the DNA damage response. To investigate the regulation of NF-κB activity, a mathematical model of coupled ordinary differential equations was developed and analyzed. The model describes DNA damage-induc...
This volume focuses on the computational modeling of cell signaling networks and the application of these models and model-based analysis to systems and personalized medicine. Chapters guide readers through various modeling approaches for signaling networks, new methods and techniques that facilitate model development and analysis, and new applications of signaling network modeling towards systems and personalized treatment of cancer. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computational Modeling of Signaling Networks aims to benefit a wide spectrum of readers including researchers from the biological as well as computational systems biology communities.