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Senescence-induced promoter methylation changes in atherosclerosis-related genes in vascular endothelial and smooth muscle cellsJee Yeon Kim1, Jaroslav Jelinek2, Junha Hwang1, Hye Seon Jeong1, Bong Geun Choi1, Jean-Pierre J. Issa2, Jei Kim11Neuroepigenetics Laboratory and Department of Neurology, Chungnam National University Hospital and School of Medicine, Daejeon, South Korea,2Fels Institute, Temple University, Philadelphia, PA, U.S.A.Background: We investigated whether promoter methylation changes occurred in atherosclerosis-related genes after in-vitro senescence of human vascular endothelial and smooth muscle cells. Methods: We induced in-vitro replicative senescence by subcultures of 3...
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Part 7: Contains results of U.S. Government investigation of German-based I.G. Farben international cartel organization and activities in support of Nazi and possible future German military efforts