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The path from clinical requirements to technical implementation is filtered by the translation of the modality to the technology. An important part of that filter is that the modality be safe. For that to be the case, it is imperative to understand what clinical parameters affect the safety of a treatment and then determine how the technology can affect those parameters. This book provides a practical introduction to particle therapy. It provides a thorough introduction to the technological tools and their applications and then details the components that are needed to implement them. It explains the foundations of beam production and beam delivery that serve to meet the necessary clinical r...
This volume is the first comprehensive and practical clinical reference on proton and charged particle radiotherapy. The first half of the book explains the treatment delivery systems used, offers detailed guidance on treatment planning techniques, examines key clinical issues in proton radiotherapy, and reviews recent experience with heavier charged particle radiotherapy. The second half of the book offers "how-to" information on treatment of pediatric tumors, lymphomas, and tumors of the central nervous system, eye, skull base, cervical spine, bone and soft tissue, paranasal sinus, nasal cavity, nasopharynx, oropharynx, oral cavity, salivary glands, prostate, lung, gastrointestinal tract, female reproductive tract, and breast. More than 100 full-color illustrations complement the text.
The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.
The Massachusetts General Hospital (MGH) has a history of excellence and is internationally recognized as a world class medical center, providing quality medical care, advancing medicine through clinical and laboratory research and facilitating the education of exceptional health care professionals. The Massachusetts General Hospital Radiation Oncology Department, staff, residents and fellows, past and present, concur that MGH stands for Man’s Greatest Hospital. This decidedly immodest assessment is widely viewed amongst this group as being manifestly true, and that perception is clearly reflected in a marvelous esprit de corp. Such an unequivocally positive attitude is solidly based on th...
Formal engineering methods are changing the way that software systems are - veloped.Withlanguageandtoolsupport,theyarebeingusedforautomaticcode generation, and for the automatic abstraction and checking of implementations. In the future, they will be used at every stage of development: requirements, speci?cation, design, implementation, testing, and documentation. The ICFEM series of conferences aims to bring together those interested in the application of formal engineering methods to computer systems. Researchers and practitioners, from industry, academia, and government, are encouraged to attend,andtohelpadvancethestateoftheart.Authorsarestronglyencouraged to make their ideas as accessibl...
Daniela Rus, a leading roboticist and computer scientist, explores how we can use a new generation of smart machines to help humankind. There is a robotics revolution underway. A record 3.1 million robots are working in factories right now, doing everything from assembling computers to packing goods and monitoring air quality and performance. A far greater number of smart machines impact our lives in countless other ways—improving the precision of surgeons, cleaning our homes, extending our reach to distant worlds—and we’re on the cusp of even more exciting opportunities. In The Heart and the Chip, roboticist Daniela Rus and science writer Gregory Mone provide an overview of the interc...
Cancer Treatment, Radiation Oncology, PSI, Pencil Beam Scanning, History of Medicine Modern proton therapy is saving the lives of more and more children and adults with difficult-to-treat cancers. The spectacular rise of proton therapy might never have happened if it were not for the pioneering work of the Paul Scherrer Institute – a Swiss centre founded to explore physics and the nature of matter, but which turned its understanding of basic science into applications that would benefit mankind. This is the place that pioneered a technique of delivering protons to tumours called pencil beam scanning (also known as spot scanning) – now used in nearly every proton therapy centre in the worl...
This book brings together 19 papers focusing on the application of rigorous design techniques to the development of fault-tolerant, software-based systems. It is an outcome of the REFT 2005 Workshop on Rigorous Engineering of Fault-Tolerant Systems held in conjunction with the Formal Methods 2005 conference at Newcastle upon Tyne, UK, in July 2005.
Over the last 4 years, IMRT, IGRT, SBRT: Advances in the Treatment Planning and Delivery of Radiotherapy has become a standard reference in the field. During this time, however, significant progress in high-precision technologies for the planning and delivery of radiotherapy in cancer treatment has called for a second edition to include these new developments. Thoroughly updated and extended, this new edition offers a comprehensive guide and overview of these new technologies and the many clinical treatment programs that bring them into practical use. Advances in intensity-modulated radiotherapy (IMRT), and 4D and adaptive treatment planning are clearly presented. Target localization and ima...
This book constitutes the refereed proceedings of the 22nd International Conference on Computer Safety, Reliability and Security, SAFECOMP 2003, held in Edinburgh, UK in September 2003. The 30 revised full papers presented together with two keynote talk abstracts were carefully reviewed and selected from 96 submissions. The papers are organized in topical sections on formal methods, design for dependability, security and formal methods, dependability and performance analysis, dependability of medical systems, fault tolerance, tools for dependable design, dependability of critical infrastructures, hazard and safety analysis, and design for dependability.