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Jane is a Los Angeles nurse who grew up in a Christian cult that puts celebrities on trial for their sins. Daniel is a has-been actor whose career ended when the cult family members nearly killed him for flirting with her. Eight years after a romantic meet-cute in Battery Park, both search for someone to fill the gap they imagine the other could've filled if given the chance. Jane compulsively goes on dates with every self-professed expert in art, music, and food hoping they will teach her the nuances of the culture she couldn't access in her youth. Daniel looks for a girlfriend who will accept the disabilities left from the cult attack. A loving woman will prove to Daniel's blockbuster star brother, Steve, that he's capable of a supporting role in Steve's upcoming movie and relaunching Daniel's career. When a chance encounter unexpectedly reunites them, Jane and Daniel not only see another chance at the love they lost, but an opportunity to create the lives they've always wanted. The only question is whether their families will let them.
He's gone to Italy to save her, but can he protect himself from the charms of her ex? Quinn and Larisa's first Christmas has ended with a house fire, a secret revealed, and Larisa's charismatic ex boyfriend, Lucas at the center of it all. It's become clear that Larisa and Quinn have no future together if they cannot find a way to detach Lucas from their lives, but their approaches to it diverge. Quinn goes to Italy to live with Lucas and play the seductive spy. But it's hard to say who is more seduced and how long Quinn will be able to survive under Lucas's intense spotlight. Meanwhile, Larisa works to undermine Lucas from LA. Dodging the young Russian girl Lucas has sent to blackmail her, Larisa stages a fake murder, negotiates with the CIA, and ultimately falls in with Lucas's business rival in a desperate attempt bring Lucas under control before Quinn falls too far.
In life, as in film, fight for the role you want. An aspiring film director with anger management issues is sent to therapy or lose his job. Instead of doing the hard work of improving himself, he invites his troubled celebrity therapist to stage a fake romance with him so they can manipulate the Hollywood PR machine to fix their reputations. Larisa de France-Kahn is the daughter of a model and a famous film producer born to host formal dinners an adorn the arm of a powerful man, but she's determined to thwart her fate by graduating from her psychiatry residency and practice emergency medicine as an anonymous citizen if only her mother will stop sending her on blind dates with billionaires w...
This much anticipated Third Edition provides a comprehensive presentation of the global burden and patterns of cancer occurrence, along with new developments in our understanding of cancer causation and prevention. Special attention is given to epidemiologic approaches that incorporate molecular biomarkers based on genomic and other emerging technologies, providing new insights into the role of genetic predisposition and gene-environment interactions in cancer induction. In addition, new chapters are included on social class disparities in cancer incidence and mortality, the role of obesity and physical inactivity in cancer etiology, the potential effects of electromagnetic fields and rediofrequency radiation, and the principles of cancer chemoprevention. The textbook is organized into five sections: Basic Concepts; The Magnitude of Cancer; The Causes of Cancer; Cancer by Tissue of Origin; Cancer Prevention and Control. In this new edition, Drs. David Schottenfeld and Joseph F. Fraumeni, Jr. have enlisted three distinguished Associate Editors: Drs. Jonathan Samet of Johns Hopkins University, Graham Colditz of Harvard University and Alice Whittemore of Stanford University.
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.
Numerous investigators have found increased levels of cyclooxygenase-2 (COX-2) in both pre-malignant and malignant tissues. Moreover, animals engineered to be COX-2 deficient or treated with a selective COX-2 inhibitor showed reduced tumor formation and growth. The present book reviews these findings suggesting that COX-2 is a valid molecular target for the prevention and treatment of cancer. The first chapters are devoted to the epidemiology of nonsteroidal anti-inflammatory drugs (NSAIDs) and cancer, the pharmacology of COX-2 inhibitors and the regulation of COX-2 expression in human cancers. Besides, the book contains a series of chapters examining the link between COX-2 and cancer in spe...
Nowadays, the environment looms large in the analysis of conflict in developing societies, and the precise role it plays is the subject of an ongoing debate. The de bate has moved on from the earlier, but still popular, notions of 'power struggles', 'class struggles' and 'ethnic conflicts', to a perception of conflict as the product of intense group competition for resources. Where the state controls the distribu tion of resources, itself inevitably becomes party to conflicts whose bone of con tention is access to state power as the most efficient means of gaining access to resources. The resources in question are social (health, education, transportation, communication, recreation, etc. ) a...
Hans-Jorg Senn H.-J. Senn (~) Center for Tumor Detection and Prevention, Rorschacherstr. 150, CH-9006 St. Gallen, Switzerland Clinical oncology has centered mainly on developing new strategies and a multitude of new drugs for fighting relapsing and progressive cancer during the last two decades. Furthermore, it has done this with respectable success in quite a number of neoplastic diseases such as acute leukemias and sarcomas in pediatric patients and certain types of aggressive lymphomas, as well as se lected solid tumors such as testicular cancer and choriocarcinoma in adult age. Curatively intended adjuvant chemo-and endocrine-therapies of several "main killers" among prevalent cancer typ...
Foreword by Nicola Griffith, author of Hild and Spear Too often, science fiction and fantasy stories erase—or cure—characters with disabilities. Soul Jar, edited by author and bookstore owner Annie Carl, features thirty-one stories by disabled authors, imagining such wonders as a shapeshifter on a first date, skin that sprouts orchid buds, and a cereal-box demon. An insulin pump diverts an undead mob. An autistic teen sets out to discover the local cranberry bog’s sinister secret. A pizza delivery on Mars goes wrong. This thrillingly peculiar collection sparkles with humor, heart, and insight, all within the context of disability representation.