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The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivation methods in a comprehensive and comparative manner, with most of the authors coming from the industry itself. Depending on the maturity of the technology, the chapters address in turn the expression system, basic process design, key factors affecting process economics, plant and bioreactor design, and regulatory aspects.
Every ecosystem is a complex organization of carefully mixed life forms; a dynamic and particularly sensible system. Consequently, their progressive decline may accelerate climate change and vice versa, influencing flora and fauna composition and distribution, resulting in the loss of biodiversity. Climate changes effects are the principal topics of this volume. Written by internationally renowned contributors, Biodiversity loss in a changing planet offers attractive study cases focused on biodiversity evaluations and provisions in several different ecosystems, analysing the current life condition of many life forms, and covering very different biogeographic zones of the planet.
Using a number of outstanding examples, this text introduces readers to the immense variety of marine natural compounds, the methodologies to characterize them and the approaches to explore their industrial potential. Care is also taken to discuss the function and ecological context of the compounds. Carefully produced and easy to read, this book serves students and professionals wishing to familiarize themselves with the field, and is ideally suited as a course book for both industry to academia.
"The series Advances in Biochemical Engineering/Biotechnology presents critical reviews of the present and future trends in polymer and biopolymer science including chemistry, physical chemistry, physics and material science. It is addressed to all scientists at universities and in industry who wish to keep abreast of advances in the topics covered."--Title page verso.
Advances in research and development reveal the immense diversity and potential of marine genetic resources. Under international law, no specific regime applies to these complex and paradoxical objects of use. The Law of the Sea Convention sets a framework that is partly inadequate for this new category of resources. The Biodiversity Convention and the Nagoya Protocol only address the genetic resources of national areas. Patents allow their holder to exercise a monopoly on exploiting biotechnological creations to extensive claims, questioning the common nature of biodiversity and related knowledge. They hinder research and the objectives of biodiversity law. The legal and practical rules of ...
The Exploitation of Marine Genetic Resources in Areas beyond National Jurisdiction by Valérie Wyssbrod begins by identifying the legal regime applicable to these underexploited resources which offer vast potential for the development of new drugs, bioplastics, depolluting products and other innovations. The author then outlines provisions for a new treaty, currently under discussion at the UN and presents alternatives to a new regime including revised legal instruments, the development of soft law and the creation of an applicable ecolabel. Dans L’exploitation des ressources génétiques marine hors juridiction nationale, Valérie Wyssbrod détermine en premier lieu le régime juridique a...
This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed in the book as well. The 1st volume mainly illustrates the molecular formula and structures of terpenoids.
This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed as well. The 3rd volume mainly illustrates the molecular formula and structures of alkaloids. .
This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed as well. The 5th volume mainly illustrates the molecular formula and structures of polyketides and steroids.