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Fighting around the globe, American soldiers were at high risk for contracting malaria, yet quinine - a natural cure - became hard to acquire. This historical study shows the roots and branches of an enormous drug development project during World War II.
New York city is a world center of science and the memorabilia presented introduce the reader to a culture of learning and of creating new knowledge, venues of great medicine, and a number of exceptional schools graduating world leaders in science.
A compelling and innovative account that reshapes our view of nineteenth-century chemistry, explaining a critical period in chemistry’s quest to understand and manipulate organic nature. According to existing histories, theory drove chemistry’s remarkable nineteenth-century development. In Molecular World, Catherine M. Jackson shows instead how novel experimental approaches combined with what she calls “laboratory reasoning” enabled chemists to bridge wet chemistry and abstract concepts and, in so doing, create the molecular world. Jackson introduces a series of practice-based breakthroughs that include chemistry’s move into lampworked glassware, the field’s turn to synthesis and...
Take a colorful walk through human ingenuity. Humans have been unpacking the earth to use pigments since cavemen times. Starting out from surface pigments for cave paintings, we’ve dug deep for minerals, mined oceans for colors and exploited the world of plants and animals. Our accidental fumbles have given birth to a whole family of brilliant blues that grace our museums, mansions and motorcars. We’ve turned waste materials into a whole rainbow of tints and hues to color our clothes, our food and ourselves. With the snip of a genetic scissor, we’ve harnessed bacteria to gift us with “greener” blue jeans and dazzling dashikis. As the pigments march on into the future, who knows wha...
Virginity--a major adolescent rite of passage--has been explored in the coming-of-age film genre for many decades. This book examines the evolution of teen movies over the past 40 years, posing crucial questions about how film shapes our cultural understanding of virginity. By surveying more than 30 mainstream and independent coming-of-age films from the 1980s to the present, it considers what types of first-time sexual experiences are represented on screen, how they are different for men and women, and whether they are subverting or reinforcing gender stereotypes. Drawing from notable teen movies such as Dirty Dancing (1987), American Pie (1999), Real Women Have Curves (2002), Lady Bird (2017), and Plan B (2021), the book identifies a progressive shift toward more sex-positive and feminist representations of first-time sexual experiences on screen. Each chapter studies how the political climate, sex education policies, and cultural norms specific to each era impact the film's release and its teenage audience.
Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.
Chemistry shapes and creates the disposition of the world's resources and provides novel substances for the welfare and hazard of our civilisation at an exponential rate. Can we model the evolution of chemical knowledge? This book not only provides a positive answer to the question, it provides the formal models and available data to model chemical knowledge as a complex dynamical system based on the mutual interaction of the social, semiotic and material systems of chemistry. These systems, which have evolved over the history, include the scientists and institutions supporting chemical knowledge (social system); theories, concepts and forms of communication (semiotic system) and the substan...
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It has become difficult to ignore the analytics movement within the NFL. An increasing number of coaches openly integrate advanced numbers into their game plans, and commentators, throughout broadcasts, regularly use terms such as air yards, CPOE, and EPA on a casual basis. This rapid growth, combined with an increasing accessibility to NFL data, has helped create a burgeoning amateur analytics movement, highlighted by the NFL’s annual Big Data Bowl. Because learning a coding language can be a difficult enough endeavor, Introduction to NFL Analytics with R is purposefully written in a more informal format than readers of similar books may be accustomed to, opting to provide step-by-step in...